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胎儿肺间质瘤:一种罕见胎儿恶性肿瘤的产前表现。

Fetal lung interstitial tumor: Prenatal presentation of a rare fetal malignancy.

作者信息

Phillips J, Blask A, DiPoto Brahmbhatt A, Lawrence A, Timofeev J, Badillo A, Andescavage N

机构信息

Department of Obstetrics and Gynecology, George Washington University School of Medicine & Health Sciences, Washington, DC, USA.

Division of Diagnostic Imaging and Radiology, Children's National Health System, Washington, DC, USA.

出版信息

J Neonatal Perinatal Med. 2019;12(4):473-477. doi: 10.3233/NPM-180059.

Abstract

Fetal lung interstitial tumor (FLIT) is a rare fetal malignancy that is typically diagnosed in the postnatal period, or, if recognized prenatally can mimic a benign lesion such as congenital pulmonary airway malformation. We present the earliest case of a FLIT tumor described by ultrasound and MRI at 26 weeks of gestation. Our case highlights features suggestive of FLIT including presentation later in gestation in combination with findings on fetal MRI such as a solid appearance with radiating curved bands of high signal within and along the periphery of the lesion (not as intensely high signal as the typical CPAM), possibly detailing a radiographic signature for these tumors. The role of betamethasone for these tumors is not known.

摘要

胎儿肺间质瘤(FLIT)是一种罕见的胎儿恶性肿瘤,通常在出生后被诊断出来,或者如果在产前被识别,可能会被误诊为良性病变,如先天性肺气道畸形。我们报告了妊娠26周时通过超声和磁共振成像(MRI)描述的最早的FLIT肿瘤病例。我们的病例突出了提示FLIT的特征,包括妊娠后期出现,并伴有胎儿MRI的表现,如病变内部和周边有呈放射状弯曲的高信号带的实性外观(不像典型的先天性肺气道畸形那样呈高强度高信号),这可能详细说明了这些肿瘤的影像学特征。倍他米松对这些肿瘤的作用尚不清楚。

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