昼夜节律睡眠-觉醒障碍。

Irregular Sleep-Wake Rhythm Disorder.

机构信息

Georgetown University, MedStar St. Mary's Sleep Lab, Georgetown University Medical Center, 3800 Reservoir Road, Washington, DC 20007, USA.

MGH Neurological Clinical Research Institute, 165 Cambridge Street, Suite 600, Boston, MA 02114, USA.

出版信息

Neurol Clin. 2019 Aug;37(3):553-561. doi: 10.1016/j.ncl.2019.04.002. Epub 2019 May 29.

DOI:10.1016/j.ncl.2019.04.002

PMID:31256789

Abstract

This article focuses on irregular sleep-wake rhythm disorder (ISWRD) and its associations with several other comorbidities. Irregular sleep-wake rhythm disorder is a circadian disorder characterized by a lack of a clear sleep-wake pattern. The disorder has yet to be fully understood from pathophysiologic perspective. Treatments are available, but there is a need for development of novel interventions. The goal of this article is to focus on multiple aspects of ISWRD.

摘要

本文重点介绍不规则睡眠-觉醒节律障碍（ISWRD）及其与其他几种合并症的关联。不规则睡眠-觉醒节律障碍是一种以缺乏清晰的睡眠-觉醒模式为特征的昼夜节律障碍。从病理生理学的角度来看，这种疾病尚未被完全理解。目前已经有治疗方法，但需要开发新的干预措施。本文的目的是重点介绍 ISWRD 的多个方面。