图片：跨性别个体的睡眠-觉醒节律障碍。
Images: Irregular sleep-wake rhythm disorder in transgender individuals.
机构信息
Lehigh Valley Fleming Neuroscience Institute, Lehigh Valley Health Network, Allentown, Pennsylvania.
出版信息
J Clin Sleep Med. 2023 Nov 1;19(11):1981-1984. doi: 10.5664/jcsm.10700.
Abstract
UNLABELLED
Growing evidence suggests that transgender individuals face a significant health disparity and are particularly vulnerable to sleep disorders. We present two patients who developed irregular sleep-wake rhythm disorder after gender reassignment and hormone replacement therapy. The growing interest in transgender health warrants further evaluation of the effects and frequency of all sleep disorders in this population. Efforts to address sleep disorders should consider assessing sleep disturbance in terms of sleep/wake patterns and schedules.
CITATION
Kokash A, Vendrame M. Images: irregular sleep-wake rhythm disorder in transgender individuals. . 2023;19(11):1981-1984.
摘要
未加标签
越来越多的证据表明，跨性别者面临着显著的健康差距，特别容易受到睡眠障碍的影响。我们介绍了两名在性别重置和激素替代疗法后出现不规则睡眠-觉醒节律障碍的患者。对跨性别者健康的日益关注需要进一步评估该人群中所有睡眠障碍的影响和频率。解决睡眠障碍的努力应考虑根据睡眠/觉醒模式和时间表评估睡眠障碍。
参考文献
Kokash A, Vendrame M. 图片：跨性别者的不规则睡眠-觉醒节律障碍。. 2023;19(11):1981-1984.
相似文献
1
Images: Irregular sleep-wake rhythm disorder in transgender individuals.图片：跨性别个体的睡眠-觉醒节律障碍。
J Clin Sleep Med. 2023 Nov 1;19(11):1981-1984. doi: 10.5664/jcsm.10700.
2
Behaviorally and environmentally induced non-24-hour sleep-wake rhythm disorder in sighted patients.视障患者的行为和环境诱发的非 24 小时睡眠-觉醒节律障碍。
J Clin Sleep Med. 2022 Feb 1;18(2):453-459. doi: 10.5664/jcsm.9612.
3
Clinical Practice Guideline for the Treatment of Intrinsic Circadian Rhythm Sleep-Wake Disorders: Advanced Sleep-Wake Phase Disorder (ASWPD), Delayed Sleep-Wake Phase Disorder (DSWPD), Non-24-Hour Sleep-Wake Rhythm Disorder (N24SWD), and Irregular Sleep-Wake Rhythm Disorder (ISWRD). An Update for 2015: An American Academy of Sleep Medicine Clinical Practice Guideline.内源性昼夜节律性睡眠-觉醒障碍治疗临床实践指南：早睡-早起型睡眠障碍（ASWPD）、晚睡-晚起型睡眠障碍（DSWPD）、非24小时睡眠-觉醒节律障碍（N24SWD）和不规则睡眠-觉醒节律障碍（ISWRD）。2015年更新版：美国睡眠医学会临床实践指南。
J Clin Sleep Med. 2015 Oct 15;11(10):1199-236. doi: 10.5664/jcsm.5100.
4
Circadian Rhythm Sleep-Wake Disorders.昼夜节律性睡眠-觉醒障碍
Continuum (Minneap Minn). 2017 Aug;23(4, Sleep Neurology):1051-1063. doi: 10.1212/CON.0000000000000499.
5
Irregular Sleep-Wake Rhythm Disorder.昼夜节律睡眠-觉醒障碍。
Neurol Clin. 2019 Aug;37(3):553-561. doi: 10.1016/j.ncl.2019.04.002. Epub 2019 May 29.
6
Irregular Sleep-Wake Rhythm Disorder.不规则睡眠-清醒节律障碍
Sleep Med Clin. 2015 Dec;10(4):517-22. doi: 10.1016/j.jsmc.2015.08.005. Epub 2015 Sep 16.
7
Workshop report. Circadian rhythm sleep-wake disorders: gaps and opportunities.工作坊报告。昼夜节律睡眠-觉醒障碍：差距与机遇。
Sleep. 2021 May 14;44(5). doi: 10.1093/sleep/zsaa281.
8
Treatment of a patient with a circadian sleep-wake disorder using a combination of melatonin and metoprolol.采用褪黑素和美托洛尔联合治疗一位昼夜节律睡眠-觉醒障碍患者。
J Clin Sleep Med. 2021 Oct 1;17(10):2121-2124. doi: 10.5664/jcsm.9410.
9
Irregular sleep-wake rhythm disorder: From the pathophysiologic perspective to the treatment.
Handb Clin Neurol. 2025;206:71-87. doi: 10.1016/B978-0-323-90918-1.00006-X.
10
Safety and Efficacy of Lemborexant in Patients With Irregular Sleep-Wake Rhythm Disorder and Alzheimer's Disease Dementia: Results From a Phase 2 Randomized Clinical Trial.仑美曲勃在伴有不规则睡眠-觉醒节律障碍的阿尔茨海默病痴呆患者中的安全性和疗效：一项 2 期随机临床试验的结果。
J Prev Alzheimers Dis. 2021;8(1):7-18. doi: 10.14283/jpad.2020.69.
引用本文的文献
1
Cross-Sex Hormone Therapy Is Associated With Loss of Circadian Rhythm in the Male Rat.跨性别激素疗法与雄性大鼠昼夜节律丧失有关。
Hypertension. 2025 Feb;82(2):241-254. doi: 10.1161/HYPERTENSIONAHA.124.23901. Epub 2024 Dec 5.
本文引用的文献
1
Examining the role of problematic drug use in the relationship between discrimination and sleep disturbance in transgender and nonbinary individuals.探讨问题药物使用在跨性别和非二元个体中歧视与睡眠障碍关系中的作用。
Addict Behav. 2022 Dec;135:107459. doi: 10.1016/j.addbeh.2022.107459. Epub 2022 Aug 11.
2
Gender identity and transition: relationships with sleep disorders in US youth.性别认同与转变：美国青少年睡眠障碍的相关研究
J Clin Sleep Med. 2022 Nov 1;18(11):2553-2559. doi: 10.5664/jcsm.10158.
3
Sleep disturbances, circadian activity, and nocturnal light exposure characterize high risk for and current depression in adolescence.睡眠障碍、昼夜节律活动和夜间光照暴露是青少年中高风险和当前抑郁的特征。
Sleep. 2022 Jul 11;45(7). doi: 10.1093/sleep/zsac104.
4
Associations Between Transgender Identity, Sleep, Mental Health and Suicidality Among a North American Cohort of College Students.北美大学生群体中跨性别身份认同、睡眠、心理健康与自杀倾向之间的关联
Nat Sci Sleep. 2021 Mar 16;13:383-398. doi: 10.2147/NSS.S286131. eCollection 2021.
5
Gender Dysphoria, Mental Health, and Poor Sleep Health Among Transgender and Gender Nonbinary Individuals: A Qualitative Study in New York City.跨性别者和性别非二元者中的性别焦虑、心理健康与睡眠质量差：纽约市的一项定性研究
Transgend Health. 2020 Mar 16;5(1):59-68. doi: 10.1089/trgh.2019.0007. eCollection 2020 Mar 1.
6
The Effects of Transgender Hormone Therapy on Sleep and Breathing: A Case Series. transgender 激素治疗对睡眠和呼吸的影响：病例系列。
J Clin Sleep Med. 2019 Oct 15;15(10):1529-1533. doi: 10.5664/jcsm.7992.
7
Reduction in Mental Health Treatment Utilization Among Transgender Individuals After Gender-Affirming Surgeries: A Total Population Study.跨性别个体接受性别肯定手术后心理健康治疗利用率降低：一项全人群研究。
Am J Psychiatry. 2020 Aug 1;177(8):727-734. doi: 10.1176/appi.ajp.2019.19010080. Epub 2019 Oct 4.
8
Hierarchical and Mediation Analysis of Disparities in Very Short Sleep among Sexual Minority Youth in the U.S., 2015.美国性少数青年极短睡眠差异的层次和中介分析，2015 年。
Behav Sleep Med. 2020 Jul-Aug;18(4):433-446. doi: 10.1080/15402002.2019.1607738. Epub 2019 May 9.
9
Circadian Rhythm Sleep Disorder: Irregular Sleep Wake Rhythm Type.昼夜节律性睡眠障碍：不规则睡眠-觉醒节律型。
Sleep Med Clin. 2009 Jun 1;4(2):213-218. doi: 10.1016/j.jsmc.2009.01.009.
10
Sleep disturbances and depression: risk relationships for subsequent depression and therapeutic implications.睡眠障碍与抑郁症：后续抑郁症的风险关系及治疗意义。
Dialogues Clin Neurosci. 2008;10(4):473-81. doi: 10.31887/DCNS.2008.10.4/plfranzen.
Zotero 插件