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同种异体角膜组织移植替代脱出的角膜内环:病例系列

Allogenic corneal tissue transplantation in substitution for extruded intracorneal rings: A case series.

作者信息

Daoud R C, Sammouh F K, Baban T A, Warrak J E, Warrak E L

机构信息

Department of Ophthalmology, Saint-George Hospital, University Medical Center, Beirut, Lebanon.

Department of Ophthalmology, Saint-George Hospital, University Medical Center, Beirut, Lebanon; Advanced Eye Care Hospital, Naccache, Lebanon.

出版信息

J Fr Ophtalmol. 2019 Dec;42(10):1090-1093. doi: 10.1016/j.jfo.2019.05.028. Epub 2019 Jun 27.

Abstract

We describe a case series of four eyes of four keratoconus patients with extruded intracorneal ring segments (ICRS) in whom donor corneal tissue was used to substitute for the extruded ICRS in an attempt to preserve its effect. In all patients, the extruded intracorneal ring was removed through the exposed area. Donor corneal tissue (tailored to the size and shape of the ICRS) was inserted into the empty ICRS tunnel and fixed in place using 10-0 nylon sutures. At three months follow-up, all patients had a healed graft and displayed a stable Kmax, best corrected visual acuity (BCVA) and corneal topography comparable to the preoperative values. Replacing extruded intracorneal rings with donor tissue grafts in keratoconus patients appears to be a promising technique in preserving the effect of the corneal ring and possibly in treating primary keratoconus with donor tissue segments. Refinement of the technique, longer follow-up, and a larger study population is warranted.

摘要

我们描述了一个病例系列,涉及四名圆锥角膜患者的四只眼睛,这些眼睛的角膜内环段(ICRS)出现了挤出情况,我们使用供体角膜组织替代挤出的ICRS,试图保留其效果。在所有患者中,通过暴露区域移除挤出的角膜内环。将供体角膜组织(根据ICRS的尺寸和形状定制)插入空的ICRS隧道,并使用10-0尼龙缝线固定到位。在三个月的随访中,所有患者的移植片均已愈合,并且Kmax、最佳矫正视力(BCVA)和角膜地形图均稳定,与术前值相当。在圆锥角膜患者中用供体组织移植替代挤出的角膜内环,似乎是一种有前景的技术,可保留角膜环的效果,并可能用供体组织段治疗原发性圆锥角膜。该技术需要进一步完善、更长时间的随访以及更大的研究人群。

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