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圆锥角膜患者角膜内环植入术前地形图指数对视觉增益的影响

Effects of Preoperative Topometric Indices on Visual Gain After Intracorneal Ring Segment Implantation For Keratoconus.

作者信息

Utine Canan Asli, Durmaz Engin Ceren, Ayhan Ziya

机构信息

Department of Ophthalmology (C.A.U., C.D.E., Z.A.), Cornea Division, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey; and Dokuz Eylul University (C.A.U.), Izmir International Biomedicine and Genome Institute, Izmir, Turkey.

出版信息

Eye Contact Lens. 2018 Nov;44 Suppl 2:S387-S391. doi: 10.1097/ICL.0000000000000490.

Abstract

OBJECTIVES

To assess the corneal topometric parameters that can be predictive for better visual gain after intracorneal ring segment (ICRS) implantation in eyes with keratoconus.

METHODS

A total of 42 eyes of 32 patients who underwent ICRS implantation at Dokuz Eylul University, Deparment of Ophthalmology, Cornea Divison were included. Changes in uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), refractive errors, and corneal topometric indices measured using Scheimpflug topography (Pentacam, Oculus) were evaluated retrospectively.

RESULTS

After creation of intrastromal tunnels of 5.01±0.03 mm inner diameter, 5.71±0.03 mm outer diameter and at 384.21±34.12 μm depth, 1 or 2 ICRS of 150 to 350 µm thickness and 90 to 210° arc length were implanted. Preoperative UDVA of 0.09±0.10 and CDVA of 0.29±0.14 Snellen lines improved postoperatively to 0.42±0.26 and 0.62±0.24, respectively (P<0.001 for both). Preoperative spherical equivalent of -6.35±4.58D and refractive astigmatism of -5.89±2.40D decreased to -3.59±3.86 and -2.25±1.66D, retrospectively (P<0.001 for both). Strong negative correlations were detected between preoperative mean simulated keratometry (SimKavg)/index of surface variance (ISV) and changes in UDVA/CDVA (P<0.01, for all). Postoperative change in ISV was positively correlated with thicknesses of implanted rings. Change in topographical keratoconus classification was positively and change in index of vertical asymmetry was negatively correlated with number of implanted rings (P<0.05 for all).

CONCLUSIONS

Preoperative ISV value seems to be beneficial in predicting visual gain after ICRS implantation, in addition to SimKavg. Future work on new nomograms for ICRS selection that include ISV, besides refractive, topographic, and cone location data, is warranted.

摘要

目的

评估圆锥角膜患者角膜基质环植入术后可预测更好视力提高的角膜地形图参数。

方法

纳入在多库兹艾吕尔大学眼科角膜科接受角膜基质环植入术的32例患者的42只眼。回顾性评估使用眼前节分析系统(Pentacam,Oculus)测量的未矫正远视力(UDVA)、矫正远视力(CDVA)、屈光不正和角膜地形图指数的变化。

结果

制作内径5.01±0.03mm、外径5.71±0.03mm、深度384.21±34.12μm的基质隧道后,植入1或2个厚度为150至350μm、弧长为90至210°的角膜基质环。术前UDVA为0.09±0.10 Snellen视力表行,CDVA为0.29±0.14 Snellen视力表行,术后分别提高至0.42±0.26和0.62±0.24(两者P均<0.001)。术前等效球镜度为-6.35±4.58D,屈光性散光为-5.89±2.40D,术后分别降至-3.59±3.86和-2.25±1.66D(两者P均<0.001)。术前平均模拟角膜曲率(SimKavg)/表面变异指数(ISV)与UDVA/CDVA的变化之间存在强负相关(所有P均<0.01)。术后ISV的变化与植入环的厚度呈正相关。地形学圆锥角膜分类的变化与植入环的数量呈正相关,垂直不对称指数的变化与植入环的数量呈负相关(所有P均<0.05)。

结论

除SimKavg外,术前ISV值似乎有助于预测角膜基质环植入术后的视力提高。有必要开展未来工作,制定新的角膜基质环选择列线图,其中除屈光、地形和圆锥位置数据外,还应包括ISV。

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