Ciavarro Giovanni, Bozzetti Francesca, Falcioni Maurizio
Department of Medicine and Surgery, Unit of Otolaryngology and Otoneurosurgery, University-Hospital of Parma, Parma, Italy.
Department of Medicine and Surgery, Unit of Neuroradiology, University-Hospital of Parma, Parma, Italy.
J Int Adv Otol. 2019 Dec;15(3):469-471. doi: 10.5152/iao.2019.6540.
Jugular foramen (JF) metastasis is rare and often presents as JF syndrome. A 73-year-old male complained of left-sided mastoid pain that irradiated to the neck since the past 3 months. Onset of facial nerve (FN) palsy and persistence of the symptomatology despite corticosteroid therapy demanded radiologic evaluation. Computed tomography and magnetic resonance imaging showed a wide osteolytic lesion of the left JF with involvement of the third segment of the FN. The patient underwent transmastoid incisional biopsy. Histopathological examination showed an adenocarcinoma that was suggested to be of respiratory origin. A primary pulmonary lesion and metastasis to other sits were detected. The patient died 1 month after the initiation of the chemotherapy. Persistent mastoid pain and progressive FN palsy must be considered indicative of JF malignant lesions. Despite early diagnosis, secondary lesions of the JF are characterized by a poor prognosis; however, accurate diagnosis may avoid unnecessary aggressive surgery.
颈静脉孔（JF）转移瘤罕见，常表现为颈静脉孔综合征。一名73岁男性，自述近3个月来左侧乳突疼痛并向颈部放射。出现面神经（FN）麻痹，尽管接受了皮质类固醇治疗，但症状持续存在，因此需要进行影像学评估。计算机断层扫描和磁共振成像显示左侧颈静脉孔有广泛的骨质溶解病变，累及面神经第三段。患者接受了经乳突切开活检。组织病理学检查显示为腺癌，提示为呼吸道起源。检测到原发性肺部病变并转移至其他部位。患者在化疗开始1个月后死亡。持续性乳突疼痛和进行性面神经麻痹必须被视为颈静脉孔恶性病变的指征。尽管早期诊断，但颈静脉孔继发性病变的预后较差；然而，准确的诊断可以避免不必要的激进手术。
