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印度北部一家三级保健医院 10 年来死产发生率的病因学和趋势:一项回顾性研究。

Aetiology and trends of rates of stillbirth in a tertiary care hospital in the north of India over 10 years: a retrospective study.

机构信息

Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

BJOG. 2019 Aug;126 Suppl 4:14-20. doi: 10.1111/1471-0528.15850. Epub 2019 Aug 13.

DOI:10.1111/1471-0528.15850
PMID:31257693
Abstract

OBJECTIVE

To analyse the aetiology of stillbirth and its changing trends in a single tertiary care referral institute of northern India over a 10-year period (2007-2016).

DESIGN

Retrospective study.

SETTING

Tertiary care hospital in the north of India.

SAMPLE

Medical records of all mothers who delivered a stillborn at the institute.

METHODS

Data was collected from monthly and annual perinatal audits and causes of stillbirths were classified using Simplified CODAC classification. Annual reduction rate was calculated by linear regression analysis and Cusick test for the changing trends over 9 years.

MAIN OUTCOME MEASURES

Of 54 160 births, 3678 babies were stillborn. Over 9 years, the annual stillbirth rate has reduced significantly from 73.6 to 62.0 per 1000 total births with an average annual reduction rate of 1%. The most common causes of stillbirths were hypertensive disorders of pregnancy (27.6%), antepartum haemorrhage (19.5%), and congenital anomalies (9.3%).

CONCLUSION

The annual reduction rate (1%) of stillbirth remains low. The aetiology of stillbirths remains unchanged over a 10-year period and hypertensive disorder of pregnancy remains the single most preventable cause of stillbirth.

TWEETABLE ABSTRACT

Analysis of stillbirths over a 10-year period in an Indian institute showed a high but declining trend with annual reduction rate of 1%.

摘要

目的

分析印度北部一家三级转诊医院 10 年来(2007-2016 年)死胎的病因及其变化趋势。

设计

回顾性研究。

地点

印度北部的一家三级保健医院。

样本

该机构所有死产母亲的病历。

方法

数据来自每月和年度围产期审计,使用简化 CODAC 分类法对死胎原因进行分类。通过线性回归分析和 Cusick 检验计算 9 年来的变化趋势的年减少率。

主要观察指标

在 54160 例分娩中,有 3678 例婴儿死产。9 年来,总出生人数的死产率从每 1000 例 73.6 例显著下降到 62.0 例,平均年下降率为 1%。死产最常见的原因是妊娠高血压疾病(27.6%)、产前出血(19.5%)和先天性异常(9.3%)。

结论

死产的年减少率(1%)仍然较低。10 年来,死产的病因没有变化,妊娠高血压疾病仍然是唯一可预防的死产原因。

推特摘要

对印度一家医院 10 年来的死产情况进行分析,显示出高但呈下降趋势,年减少率为 1%。

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