Sussman Eric S, Ho Allen, Pendharkar Arjun V, Tharin Suzanne
Neurosurgery, Stanford University School of Medicine, Stanford, USA.
Cureus. 2019 Apr 20;11(4):e4509. doi: 10.7759/cureus.4509.
The treatment of painful spinal metastases in patients with limited life-expectancy, significant perioperative risks, and poor bone quality poses a surgical challenge. Recent advances in minimal-access spine surgery allow for the surgical treatment of patients previously considered not to be operative candidates. The addition of fenestrated screws for cement augmentation to existing image-guided percutaneous pedicle screw fixation can enhance efficiency, decrease risk of hardware complications, and improve back pain in this patient population. The patient is a 70-year-old man with severe axial back pain due to metastatic prostate cancer and L5 pathologic fractures not amenable to kyphoplasty. In the setting of a 6-12-month life-expectancy, the primary goal of surgery was relief of back pain associated with instability with minimal operative morbidity and post-operative recovery time. This was achieved with an internal fixation construct including percutaneously placed cement-augmented fenestrated pedicle screws at L4 and S1. The patient was discharged to home on post-operative day 1 with substantial improvement of his low back pain. Image-guided, percutaneous placement of fenestrated, cement-augmented pedicle screws is an emerging treatment for back pain associated with metastasis. Fenestrated screws allow for integrated cement augmentation. The minimal associated blood loss and recovery time make this approach an option even for patients with limited life-expectancy. This is the first report of utilization of this technique for the veteran population.
对于预期寿命有限、围手术期风险高且骨质较差的患者,疼痛性脊柱转移瘤的治疗颇具手术挑战。微创脊柱手术的最新进展使先前被认为不适合手术的患者能够接受手术治疗。在现有的影像引导下经皮椎弓根螺钉固定基础上增加带孔螺钉用于骨水泥强化,可提高效率、降低内固定并发症风险并改善这类患者的背痛。该患者为一名70岁男性,因转移性前列腺癌导致严重的轴向背痛及L5病理性骨折,无法进行椎体后凸成形术。鉴于预期寿命为6至12个月,手术的主要目标是缓解与不稳定相关的背痛,同时将手术发病率和术后恢复时间降至最低。通过在L4和S1处经皮置入骨水泥强化带孔椎弓根螺钉的内固定结构实现了这一目标。患者术后第1天出院,腰痛明显改善。影像引导下经皮置入带孔骨水泥强化椎弓根螺钉是治疗与转移相关背痛的一种新兴方法。带孔螺钉可实现骨水泥强化一体化。相关失血和恢复时间极少,这使得该方法即使对于预期寿命有限的患者也是一种选择。这是该技术应用于退伍军人人群的首例报告。