Panyu Central Hospital, Cancer Institute of Panyu, Guangzhou, China.
Head Neck. 2019 Sep;41(9):E153-E158. doi: 10.1002/hed.25859. Epub 2019 Jul 2.
Metastases to the bones, lungs, and liver are common in patients with nasopharyngeal carcinoma (NPC) but not to the brain and frontal bone (B + FB).
We describe a patient with NPC with B + FB metastasis. He received two cycles of palliative chemotherapy (gemcitabine and cisplatin) and then radiotherapy (60 Gy) for B + FB metastasis. A literature review of previous cases was also undertaken.
Follow-up 6 months after completion of chemotherapy and radiotherapy showed that our patient experienced a complete response without signs of NPC progression.
B + FB metastases from NPC are uncommon. Our case highlights the diagnostic and treatment difficulties clinicians face when dealing with patients with uncommon sites of metastasis. Optimal adjuvant therapy followed by local radiotherapy might elicit long survival in patients with NPC with uncommon sites of metastasis.
鼻咽癌（NPC）患者常见骨骼、肺和肝转移，但不常见脑部和额骨转移（B+FB）。
我们描述了一位 NPC 伴 B+FB 转移患者。他接受了两周期姑息化疗（吉西他滨和顺铂），然后针对 B+FB 转移行放疗（60Gy）。我们还对以往病例进行了文献回顾。
化疗和放疗完成后 6 个月的随访显示，我们的患者完全缓解，无 NPC 进展迹象。
NPC 的 B+FB 转移并不常见。我们的病例强调了临床医生在处理罕见转移部位患者时面临的诊断和治疗困难。对于 NPC 伴罕见转移部位的患者，采用最佳辅助治疗加局部放疗可能会产生长期生存。
