[抑氨肽酶B在胃癌手术中的前瞻性随机对照研究]
[Prospective randomized controlled study of bestatin in gastric cancer surgery].
作者信息
Yoshinaka K, Tanaka T, Takagami S, Saeki T, Nishiyama M, Toge T, Niimoto M, Hattori T
机构信息
Dept. of Surgery, Hiroshima University.
出版信息
Gan To Kagaku Ryoho. 1988 Mar;15(3):493-8.
The effectiveness of bestatin combined with mitomycin C and tegafur as an adjuvant to surgery for gastric cancer was investigated in a prospective randomized controlled study. All patients underwent curative gastrectomy during the period from November 1980 to April 1984. Five-year survival rate revealed no significant difference between groups with or without bestatin. The effectiveness of bestatin was suggested in postoperative peritoneal recurrence in cases with positive histological invasion into the veins of the stomach wall.
在一项前瞻性随机对照研究中，研究了贝司他汀联合丝裂霉素C和替加氟作为胃癌手术辅助治疗的有效性。所有患者在1980年11月至1984年4月期间接受了根治性胃切除术。五年生存率显示，使用或不使用贝司他汀的组间无显著差异。对于胃壁静脉组织学浸润阳性的病例，贝司他汀在术后腹膜复发方面显示出有效性。
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