具有聚集诱导发光特性的硼氮烷配合物的简便构建及其在特定脂滴成像中的应用。
Facile construction of boranil complexes with aggregation-induced emission characteristics and their specific lipid droplet imaging applications.
机构信息
Key Laboratory of Macromolecular Science of Shaanxi Province, Key Laboratory of Applied Surface and Colloid Chemistry of Ministry of Education, Key Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, and School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi'an 710119, China.
出版信息
Chem Commun (Camb). 2019 Jul 16;55(58):8494-8497. doi: 10.1039/c9cc04041b.
A rational strategy was reported to construct boranil complexes (DPFB derivatives) with unique aggregation-induced emission effects by installing phenyl rings in the anil ligand as the intramolecular rotors. In view of the good biocompatibility and suitable lipophilicity, DPFB derivatives can serve as excellent fluorescent probes for specific imaging of lipid droplets in living cells and yolk lipids in zebrafish.
报道了一种合理的策略，通过在苯胺配体中安装苯环作为分子内转子，构建具有独特聚集诱导发射效应的硼烷二吡咯甲川（DPFB）衍生物。鉴于良好的生物相容性和适宜的亲脂性，DPFB 衍生物可用作活细胞中脂滴和斑马鱼卵黄脂质的特异性成像的优良荧光探针。
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