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抗N-甲基-D-天冬氨酸受体脑炎:急诊科的一项具有挑战性的诊断

Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Challenging Diagnosis in the Emergency Department.

作者信息

Zhao Bailey, Nelson David G

机构信息

From the Department of Emergency Medicine, University of Nevada School of Medicine.

University Medical Center, Las Vegas, NV.

出版信息

Pediatr Emerg Care. 2019 Sep;35(9):e159-e161. doi: 10.1097/PEC.0000000000001853.

DOI:10.1097/PEC.0000000000001853
PMID:31268960
Abstract

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an underdiagnosed disease that has been described thus far only in case series. Patients, the majority of which are females, develop neuropsychiatric symptoms that can often be misdiagnosed as purely psychiatric illness. Although teratomas are nearly pathognomonic for anti-NMDAR encephalitis, these are less common in children and males. This case illustrates some common features of anti-NMDAR encephalitis and some of the challenges in diagnosis.

摘要

抗N-甲基-D-天冬氨酸受体(NMDAR)脑炎是一种诊断不足的疾病,迄今为止仅在病例系列中有所描述。患者大多数为女性,会出现神经精神症状,这些症状常常被误诊为单纯的精神疾病。虽然畸胎瘤几乎是抗NMDAR脑炎的特征性表现,但在儿童和男性中较少见。本病例说明了抗NMDAR脑炎的一些常见特征以及诊断中的一些挑战。

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引用本文的文献

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Anti-N-methyl-D-aspartate receptor encephalitis: characteristics and rapid diagnostic approach in the emergency department.抗 N-甲基-D-天冬氨酸受体脑炎:急诊科的特征和快速诊断方法。
BMC Neurol. 2022 Jun 18;22(1):224. doi: 10.1186/s12883-022-02752-9.