Simonin Alexandre, Maduri Rodolfo, Viaroli Edoardo, Levivier Marc, Daniel Roy Thomas, Messerer Mahmoud
Neurosurgery, Department of Clinical Neurosciences, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland,
Neurosurgery, Department of Clinical Neurosciences, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
Pediatr Neurosurg. 2019;54(4):223-227. doi: 10.1159/000500767. Epub 2019 Jul 3.
Crouzon syndrome represents the most common syndromic craniosynostosis. Ocular complications are frequent, including papilledema and optic atrophy, often related to increased intracranial pressure (ICP). However, there is a poor correlation between ICP normalization and resolution of papilledema. We describe the case of a 6-month-old infant who presented with typical phenotypic features of Crouzon syndrome. Pre- and postoperative ICP monitoring was used. Papilledema persisted despite ICP improvement after decompressive craniectomy. Possible causes of papilledema in this syndromic craniosynostosis are discussed in light of the existing literature.
克鲁宗综合征是最常见的综合征性颅缝早闭症。眼部并发症很常见，包括视乳头水肿和视神经萎缩，常与颅内压升高（ICP）有关。然而，颅内压恢复正常与视乳头水肿消退之间的相关性较差。我们描述了一名6个月大婴儿的病例，该婴儿具有克鲁宗综合征的典型表型特征。采用了术前和术后颅内压监测。尽管减压颅骨切除术后颅内压有所改善，但视乳头水肿仍持续存在。结合现有文献讨论了这种综合征性颅缝早闭症中视乳头水肿的可能原因。
