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[大鼠异位伤害性信息向背侧网状核亚核神经元的汇聚]

[Convergence of heterotopic nociceptive information onto neurons of the subnucleus reticularis dorsalis in the rat].

作者信息

Villanueva L, Bouhassira D, Bing Z, Le Bars D

机构信息

Unité de Recherches de Neurophysiologie pharmacologique de l'I.N.S.E.R.M., Paris.

出版信息

C R Acad Sci III. 1988;306(1):25-30.

PMID:3126983
Abstract

The nature of stimuli that activate neurones located within the Subnucleus Reticularis Dorsalis (SRD) was determined. These neurones do not respond to visual, auditory or proprioceptive stimuli but are preferentially or even exclusively activated by noxious stimuli applied to any part of the body; only neurones of a sub-group have a predominantly contralateral activation. All the neurones were exclusively activated by stimulation of A delta or A delta and C afferent fibres. These observations suggest that this well-delimited reticular structure is specifically involved in the processing of nociceptive information.

摘要

确定了激活位于背侧网状亚核(SRD)内神经元的刺激的性质。这些神经元对视觉、听觉或本体感觉刺激无反应,但优先甚至仅由施加于身体任何部位的有害刺激激活;只有一个亚组的神经元主要有对侧激活。所有神经元仅由Aδ或Aδ和C传入纤维的刺激激活。这些观察结果表明,这个界限分明的网状结构特别参与伤害性信息的处理。

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