División de Ciencias de la Salud, Universidad de Quintana Roo, Av. Erick Paolo Martínez S/N esquina Av 4 de marzo. Colonia Magisterial, 77039, Chetumal, Quintana Roo, Mexico.
Laboratorio Efectos Terapéuticos de los Canabinoides, Subdirección de Investigación Biomédica, Hospital General Dr. Manuel Gea González, Ciudad de México, Mexico.
Arch Sex Behav. 2019 Nov;48(8):2617-2631. doi: 10.1007/s10508-019-01483-2. Epub 2019 Jul 3.
Although sex drive is present in many animal species, sexual behavior is not static and, like many other behaviors, can be modified by experience. This modification relies on synaptic plasticity, a sophisticated mechanism through which neurons change how they process a given stimulus, and the neurophysiological basis of learning. This review addresses the main plastic effects of steroid sex hormones in the central nervous system (CNS) and the effects of sexual experience on the CNS, including effects on neurogenesis, intracellular signaling, gene expression, and changes in dendritic spines, as well as behavioral changes.
尽管性欲存在于许多动物物种中，但性行为并不是一成不变的，它可以像许多其他行为一样，通过经验进行改变。这种改变依赖于突触可塑性，这是一种复杂的机制，通过这种机制，神经元改变它们处理特定刺激的方式，以及学习的神经生理学基础。这篇综述讨论了类固醇性激素在中枢神经系统（CNS）中的主要可塑性效应，以及性经验对 CNS 的影响，包括对神经发生、细胞内信号转导、基因表达和树突棘变化的影响，以及行为变化。
