King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia.
College of Medicine, Al-Faisal University, Riyadh, Saudi Arabia.
Eur J Haematol. 2019 Sep;103(3):152-163. doi: 10.1111/ejh.13271. Epub 2019 Jul 4.
Follicular Lymphoma (FL) is an indolent lymphoma and may have various clinical courses. Worldwide, FL is the second most common non-Hodgkin lymphoma (NHL) type after diffuse large B-cell lymphoma. In this review article, the author is discussing relevant diagnostic tools, prognostic factors, and updated study results on the management of patients with newly diagnosed and relapsed/refractory FL. Controversies in the treatment, maintenance therapy, stem cell transplantation, and novel treatment approaches will be comprehensively discussed.
滤泡性淋巴瘤(FL)是一种惰性淋巴瘤,可能有多种临床病程。在全球范围内,FL 是继弥漫性大 B 细胞淋巴瘤之后第二常见的非霍奇金淋巴瘤(NHL)类型。在这篇综述文章中,作者讨论了新诊断和复发/难治性 FL 患者管理的相关诊断工具、预后因素和最新研究结果。治疗中的争议、维持治疗、干细胞移植和新的治疗方法将被全面讨论。