From the Nuclear Medicine Department, Istanbul Research and Training Hospital.
Pathology Department.
Clin Nucl Med. 2019 Aug;44(8):e499-e500. doi: 10.1097/RLU.0000000000002594.
A 66-year-old man with neuroendocrine tumor originating from midgut was referred to Ga-DOTATATE PET/CT imaging for restaging postoperatively. No suspicious uptake regarding residual primary tumoral involvement was seen. But there was diffuse high uptake in prostate gland suggestive of prostatitis or secondary primary tumoral lesion. Concurrent prostate-specific antigen level was 5.02 ng/mL (range, 0-4 ng/mL), C-reactive protein level was 8.25 mg/L (range, <5 mg/L), and white blood cell count was 6.83 × 10/μL (range, 3.9-10.9 × 10/μL). Diagnosis of active chronic prostatitis was achieved by core biopsy, which is identified as potential cause for false-positive diffuse uptake on Ga-DOTATATE PET/CT.
一位 66 岁的男性,患有源自中肠的神经内分泌肿瘤,因术后复查被转诊至 Ga-DOTATATE PET/CT 成像。未见可疑的残留原发性肿瘤累及的摄取。但前列腺弥漫性高摄取,提示前列腺炎或继发性原发性肿瘤病变。同时前列腺特异性抗原水平为 5.02ng/mL(范围,0-4ng/mL),C 反应蛋白水平为 8.25mg/L(范围,<5mg/L),白细胞计数为 6.83×10/μL(范围,3.9-10.9×10/μL)。通过核心活检诊断为活动性慢性前列腺炎,这是 Ga-DOTATATE PET/CT 上出现弥漫性摄取假阳性的潜在原因。