Awoke Netsanet, Dulo Bedado, Wudneh Feven
Department of Medical Laboratory Science, Dilla University, P.O. Box 419/13, Ethiopia.
Interdiscip Perspect Infect Dis. 2019 Jun 2;2019:2154240. doi: 10.1155/2019/2154240. eCollection 2019.
TB is an infectious disease caused by the bacillus complex. It is a major public health concern causing devastating illness in millions of people each year and one of the top 10 causes of death worldwide following HIV pandemic. It demands huge costs each year for prevention, diagnosis, and treatment of TB. Global TB control progress depends on major advances in early diagnosis and treatment. Despite progress in providing diagnosis and preventive treatment of TB, big detection and treatment gaps remained with delayed diagnosis and treatment of TB especially in resource-limited countries. This is mainly because of factors related to the patient and health care system including sociodemographic, economic, and cultural barriers to accessing TB care.
The study conducted in Gedeo Zone, Southern Ethiopia, had the primary purpose of identifying the median delay in starting a correct TB treatment and the associated factors for such a delay in patients newly diagnosed with PTB in selected health facilities of Gedeo Zone, Southern Ethiopia, 2017/18.
Institutional based cross-sectional study was conducted among new pulmonary TB patients in selected health institution of Gedeo Zone, Southern Ethiopia, 2017, from October, 2017, to May, 2018. All new pulmonary TB patients who fulfill the inclusion criteria during the study period were included in the study after informed consent was obtained from the participants. Data was cleaned, coded, and entered into SPSS version 20 for analysis. A frequency for variables was calculated. Chi-square was used to screen the possible potential associated factors and multivariate analysis was used to ascertain the association between variables. All statistical tests values of p<0.05 were considered as statistically significant.
The median total in treatment of TB was 60 days. Among the total study participants, 50.9% of the participants have unacceptable/longer total delay in TB treatment. Being of female gender, not attending formal education, having rural residency, having poor knowledge of TB, having home distance >10Km from the nearest health facility, visiting nonformal health care provider, and taking antibiotic treatment before TB diagnosis empirically were identified as significant independently associated factors for unacceptable total treatment in TB.
There was higher median total delay in treatment of TB (60 days) and an overall prevalence of 50.9% unacceptable/longer total delay in treatment of TB. Female gender, rural residence, not attending formal education, visiting nonformal health facility as first health care seeking, having poor knowledge of TB, and having antibiotic treatment before TB diagnosis were identified as independent significant associated factors.
结核病是由结核杆菌复合群引起的一种传染病。它是一个重大的公共卫生问题,每年导致数百万人患上毁灭性疾病,是继艾滋病毒大流行之后全球十大死因之一。每年用于结核病预防、诊断和治疗的费用巨大。全球结核病控制进展取决于早期诊断和治疗方面的重大进展。尽管在提供结核病诊断和预防性治疗方面取得了进展,但在结核病检测和治疗方面仍存在巨大差距,尤其是在资源有限的国家,结核病的诊断和治疗存在延迟。这主要是由于与患者和医疗保健系统相关的因素,包括获得结核病治疗的社会人口、经济和文化障碍。
在埃塞俄比亚南部的格代奥地区进行的这项研究,主要目的是确定在埃塞俄比亚南部格代奥地区选定的医疗机构中,新诊断为肺结核的患者开始正确的结核病治疗的中位延迟时间以及这种延迟的相关因素,研究时间为2017/18年。
2017年10月至2018年5月,在埃塞俄比亚南部格代奥地区选定的医疗机构中,对新的肺结核患者进行了基于机构的横断面研究。在获得参与者的知情同意后,将研究期间符合纳入标准的所有新肺结核患者纳入研究。数据进行了清理、编码,并输入SPSS 20版进行分析。计算变量的频率。使用卡方检验筛选可能的潜在相关因素,并使用多变量分析确定变量之间的关联。所有p<0.05的统计检验值被认为具有统计学意义。
结核病治疗的总中位时间为60天。在所有研究参与者中,50.9%的参与者在结核病治疗中存在不可接受的/更长的总延迟。女性、未接受正规教育、居住在农村、对结核病知识了解不足、家庭距离最近的医疗机构>10公里、就诊于非正规医疗服务提供者以及在结核病诊断前经验性使用抗生素治疗被确定为结核病不可接受的总治疗的独立显著相关因素。
结核病治疗的总中位延迟时间较高(60天),总体上有50.9%的患者存在不可接受的/更长的总治疗延迟。女性、农村居住、未接受正规教育、首次寻求医疗服务时就诊于非正规医疗机构、对结核病知识了解不足以及在结核病诊断前使用抗生素治疗被确定为独立的显著相关因素。