Suppr超能文献

小儿黏连性小肠梗阻的治疗:手术时机和年龄是否重要?

Management of Pediatric Adhesive Small Bowel Obstruction: Do Timing of Surgery and Age Matter?

机构信息

School of Medicine, Baylor College of Medicine, Houston, Texas.

Division of Pediatric Surgery, Department of Surgery, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas.

出版信息

J Surg Res. 2019 Nov;243:384-390. doi: 10.1016/j.jss.2019.05.061. Epub 2019 Jul 2.

Abstract

BACKGROUND

Adhesive small bowel obstruction (ASBO) in children is generally managed with initial observation. However, no clear guidelines exist regarding indications to operate. Our purpose was to compare outcomes of ASBO management to determine whether timing of surgery and patient age should affect management.

MATERIALS AND METHODS

A retrospective review of children admitted to a tertiary care children's hospital for ASBO between 2011 and 2015 was performed. Data included demographics, imaging, operative findings, and clinical management, which were analyzed using χ test, Fischer's exact test, t-test, analysis of variance, or logistic regression when appropriate.

RESULTS

We identified 258 admissions for 202 patients. Urgent operation was performed in 12% and the rest had nonoperative management (NOM), which was successful in 54%. Patients younger than 1 y of age were more likely to require operation (odds ratio 3.71, 95% confidence interval [CI] 1.69-8.15; P < 0.01), and patients with prior ASBO were less likely to require operation (odds ratio 0.51, 95% CI 0.31-0.84; P < 0.01). At presentation, fever was most common in patients who had urgent operation (22.3% versus failure of NOM 7.6% versus successful NOM 6.6%; P = 0.02), but there were no differences in leukocytosis or abdominal pain. Excluding urgent operations, bowel resection was more common when operation was delayed more than 48 h (32.6% versus 15.3%; P = 0.04).

CONCLUSIONS

In children with adhesive small bowel obstruction, NOM can be successful, but when failure is suspected, early operation before 48 h should be considered to avoid bowel loss, especially in children younger than 1 y of age.

摘要

背景

小儿粘连性小肠梗阻(ASBO)一般采用初始观察治疗。然而,目前尚无明确的手术指征指南。我们的目的是比较 ASBO 治疗的结果,以确定手术时机和患者年龄是否会影响治疗策略。

材料与方法

回顾性分析 2011 年至 2015 年期间在一家三级儿童医院因 ASBO 住院的患儿。资料包括人口统计学、影像学、手术发现和临床管理,使用卡方检验、Fisher 确切检验、t 检验、方差分析或逻辑回归进行分析,视情况而定。

结果

我们共纳入 202 例患儿的 258 例次住院。12%的患儿接受了紧急手术,其余患儿接受了非手术治疗(NOM),其中 54%的患儿治疗成功。年龄小于 1 岁的患儿更可能需要手术(优势比 3.71,95%置信区间 [CI] 1.69-8.15;P<0.01),有过 ASBO 病史的患儿更可能无需手术(优势比 0.51,95% CI 0.31-0.84;P<0.01)。就诊时,紧急手术组患儿发热的发生率(22.3%)高于 NOM 治疗失败组(7.6%)和 NOM 治疗成功组(6.6%)(P=0.02),但白细胞增多或腹痛在各组间无差异。排除紧急手术组,手术延迟超过 48 小时时肠切除更为常见(32.6%比 15.3%)(P=0.04)。

结论

对于粘连性小肠梗阻患儿,NOM 可以成功治疗,但当怀疑治疗失败时,应在 48 小时内早期手术,避免肠管丢失,特别是对于年龄小于 1 岁的患儿。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验