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对于髋关节假体周围骨折患者,手术延迟超过 24 小时会增加早期发病率,但不会增加死亡率。

Early Morbidity but Not Mortality Increases With Surgery Delayed Greater Than 24 Hours in Patients With a Periprosthetic Fracture of the Hip.

机构信息

Department of Orthopaedic Surgery, Columbia University Medical Center, New York, NY.

出版信息

J Arthroplasty. 2019 Nov;34(11):2789-2792.e1. doi: 10.1016/j.arth.2019.06.027. Epub 2019 Jun 16.

DOI:10.1016/j.arth.2019.06.027
PMID:31279604
Abstract

BACKGROUND

Studies have identified a possible morbidity and mortality benefit with expedited time to surgery after a native hip fracture. This association after hip periprosthetic fractures (PPF) has been less clearly delineated. The purpose of this study is to assess the effect of time to surgery on rates of 30-day complications.

METHODS

The National Surgical Quality Improvement Program registry was used to identify all patients who underwent surgical intervention for hip PPF between 2005 and 2016. Patients were stratified into 2 cohorts based on time from hospital admission to surgery, either ≤24 hours (expedited) or >24 hours (non-expedited). Thirty-day outcome variables were assessed using bivariate and multivariate analyses.

RESULTS

We identified 857 patients undergoing surgical intervention for hip PPF, of whom 402 (46.9%) underwent expedited surgery and 455 (53.1%) underwent non-expedited surgery. Patients with non-expedited surgery had an average time to surgery of 2.4 days (range, 1-14 days). Multivariate analysis adjusting for differences in baseline patient characteristics revealed that patients with a non-expedited procedure had higher rates of overall complications (odds ratio [OR] = 1.72; P = .014), respiratory complications (OR = 4.15; P = .0029), urinary tract infections (OR = 2.77; P = .020), nonhome discharge (OR = 2.22; P < .001), and blood transfusions (OR = 1.86; P < .001). There was no statistical difference in mortality (P = .093). Patients with non-expedited surgery also had longer total and postoperative (+2.7 days; P < .001) length of stay.

CONCLUSION

This study did not identify any statistical difference in mortality but found an association with increased postoperative complications and non-expedited surgery for PPF. Additional prospective studies may be warranted to identify the causative factors behind this association.

摘要

背景

研究已经确定,在发生原生髋关节骨折后,尽快进行手术可以降低发病率和死亡率。然而,这种关联在髋关节假体周围骨折(PPF)患者中尚未得到明确界定。本研究旨在评估手术时间对 30 天内并发症发生率的影响。

方法

使用国家手术质量改进计划登记处(National Surgical Quality Improvement Program registry),确定了 2005 年至 2016 年间接受髋关节 PPF 手术治疗的所有患者。根据从入院到手术的时间,患者分为 2 个队列,即≤24 小时(加速)或>24 小时(非加速)。使用二变量和多变量分析评估 30 天的结果变量。

结果

我们共纳入了 857 例接受髋关节 PPF 手术治疗的患者,其中 402 例(46.9%)接受了加速手术,455 例(53.1%)接受了非加速手术。非加速手术患者的平均手术时间为 2.4 天(范围,1-14 天)。调整基线患者特征差异后的多变量分析显示,非加速手术组的总体并发症发生率较高(比值比 [OR] = 1.72;P =.014)、呼吸系统并发症(OR = 4.15;P =.0029)、尿路感染(OR = 2.77;P =.020)、非家庭出院(OR = 2.22;P <.001)和输血(OR = 1.86;P <.001)。死亡率无统计学差异(P =.093)。非加速手术患者的总住院时间和术后住院时间(+2.7 天;P <.001)也更长。

结论

本研究未发现死亡率有统计学差异,但发现与 PPF 的非加速手术相关的术后并发症发生率增加。可能需要进一步的前瞻性研究来确定这种关联背后的因果因素。

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