Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
School of Social Work, Texas State University, San Marcos, TX, USA.
J Affect Disord. 2019 Sep 1;256:541-549. doi: 10.1016/j.jad.2019.06.039. Epub 2019 Jun 30.
Among active duty service members and veterans with PTSD, depression is the most commonly diagnosed comorbid psychiatric condition. More research is warranted to investigate the relationship between PTSD and depression to improve treatment approaches. Byllesby et al. (2017) used confirmatory factor analyses in a sample of trauma-exposed combat veterans with PTSD and found that only the general distress factor, and not any specific symptom cluster of PTSD, predicted depression. This study seeks to replicate Byllesby et al. (2017) in a sample of treatment-seeking active duty soldiers.
Confirmatory factor analyses, bifactor modeling, and structural equation modeling (SEM) were used with data gathered at pretreatment and posttreatment as part of a large randomized clinical trial.
Confirmatory factor analyses and bifactor modeling demonstrated that PTSD symptom clusters, Negative Alterations in Cognition and Mood (NACM) and Alterations in Arousal and Reactivity (AAR), as well as the general distress factor significantly predicted depression at pretreatment and posttreatment.
The current study was predominantly male, limiting the generalizability to female service members with PTSD. Also, self-report measures were used, which may introduce response-bias.
The current study did not replicate Byllesby et al. (2017). Results demonstrated that the relationship between PTSD and depression among active duty service members can be explained by both transdiagnostic factors and disorder-specific symptoms.
在患有 PTSD 的现役军人和退伍军人中，抑郁症是最常见的共病精神疾病。需要更多的研究来调查 PTSD 和抑郁症之间的关系，以改善治疗方法。Byl lesby 等人（2017 年）在患有 PTSD 的创伤后暴露的退伍军人样本中使用验证性因素分析发现，只有一般困扰因素，而不是 PTSD 的任何特定症状群，预测了抑郁症。这项研究旨在在寻求治疗的现役士兵样本中复制 Byl lesby 等人（2017 年）的研究。
在作为大型随机临床试验的一部分在治疗前和治疗后收集的数据中使用验证性因素分析、双因素建模和结构方程建模（SEM）。
验证性因素分析和双因素模型表明，PTSD 症状群、负性认知和情绪改变（NACM）和觉醒和反应改变（AAR）以及一般困扰因素在治疗前和治疗后均显著预测了抑郁。
本研究主要是男性，限制了 PTSD 的女性军人的普遍性。此外，使用了自我报告的措施，这可能会引入反应偏差。
本研究没有复制 Byl lesby 等人（2017 年）的研究结果。结果表明，现役军人 PTSD 和抑郁症之间的关系可以用跨诊断因素和特定于疾病的症状来解释。
