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[新型气动控制呼吸机高频喷射通气的动物实验研究]

[Animal experiment studies of high frequency jet ventilation with a newly developed pneumatically controlled respirator].

作者信息

Klein U, Claussen D, Schubert H, Zieger M

机构信息

Klinik für Anästhesiologie und Intensivtherapie, Bereiches Medizin Friedrich-Schiller-Universität Jena/DDR.

出版信息

Z Erkr Atmungsorgane. 1987;169(3):283-90.

PMID:3128015
Abstract

The effects of high frequency jet ventilation (HFJV) were investigated in 12 mongrel dogs with normal lungs. A newly developed HFJV device with purely pneumatic regulation was used. In order to evaluate several ventilatory parameters, respiratory rate, breathing time quotient and jet emission pressure were varied. Thus, important ventilatory, hemodynamic and calculated values were recorded. Accordingly, HFJV is possible with the tested device under clinical conditions in the frequency range between 80 and 300/min, with a breathing time ratio of 1:21 to 1:1 and a driving pressure up to 0.4 MPa with an oxygen concentration of FiO2 = 0.21 to 1.0. Before clinical use, however, investigations on the damaged lung of the dog are necessary.

摘要

在12只肺部正常的杂种犬身上研究了高频喷射通气(HFJV)的效果。使用了一种新开发的具有纯气动调节功能的HFJV装置。为了评估几个通气参数,对呼吸频率、呼吸时间商和喷射发射压力进行了改变。因此,记录了重要的通气、血流动力学和计算值。相应地,在临床条件下,使用测试装置进行HFJV是可行的,频率范围为80至300次/分钟,呼吸时间比为1:21至1:1,驱动压力高达0.4MPa,氧浓度FiO2 = 0.21至1.0。然而,在临床使用之前,有必要对犬的受损肺进行研究。

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