Department of Pathology, University Hospital, Heidelberg, Germany.
Department of Obstetrics and Gynaecology, University Hospital, Heidelberg, Germany.
Breast J. 2019 Nov;25(6):1251-1253. doi: 10.1111/tbj.13436. Epub 2019 Jul 6.
Recently, it has been reported that IgG4-related disease may occur in the breast manifesting as nodular sclerosing interstitial mastitis. Here we report a case with multiple tumor-like nodules in one breast. The histologic diagnosis was established on core needle biopsies, and treatment was initiated without open biopsy. Diagnosis of IgG4-related sclerosing mastitis should be suspected in cases of tumor-like lesions on imaging with an interstitial plasma cell-rich sclerosing inflammation on histology.
最近有报道称，IgG4 相关疾病可发生于乳腺，表现为结节性硬化性间质乳腺炎。本文报道了 1 例乳腺多发病灶病例，组织学诊断基于核心针活检，未行开放性活检即开始治疗。对于影像学上表现为肿块样病变且组织学上具有丰富浆细胞的间质硬化性炎症，应疑诊 IgG4 相关硬化性乳腺炎。
