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描述加拿大三级保健中心医院病例普查中诊断性采血估计失血量的当代资料。

A contemporary description of patients' estimated blood losses from diagnostic phlebotomy in a census of hospital episodes from a Canadian tertiary care center.

机构信息

Department of Pathology and Laboratory Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

Department of Pathology and Laboratory Medicine, Nova Scotia Healthy Authority, Halifax, Nova Scotia, Canada.

出版信息

Transfusion. 2019 Sep;59(9):2849-2856. doi: 10.1111/trf.15434. Epub 2019 Jul 8.

DOI:10.1111/trf.15434
PMID:31283032
Abstract

BACKGROUND

Phlebotomy for diagnostic testing is among the commonest hospital procedures, but hospital-wide surveys of all inpatients characterizing blood draw volumes have not been published. The objectives were to characterize the daily blood volumes drawn for diagnostic testing from patients discharged from a Canadian tertiary care center, describe the daily distributions of phlebotomy volumes across service locations, and describe changes in hemoglobin (Hb) and transfusion across service locations.

STUDY DESIGN AND METHODS

Data were obtained on all patients discharged between 2012 and 2014 using linked discharge abstract and laboratory data. Cumulative daily blood volume and draw frequency were reported by service and days since admission. Changes in Hb and red blood cell (RBC) transfusion rates were reported for nontransfused and transfused patients.

RESULTS

Data were included on 59,715 subjects. Mean daily estimated blood loss varied from 8.5 ± 6.5 mL/day onward to 27.2 ± 20.0 mL/day in the intensive care unit (ICU; p < 0.001). Phlebotomy volumes were highest on the first day of admission and declined thereafter (p < 0.001). For nontransfused individuals in the first week of admission, Hb levels decreased by the highest percentage in the ICU. The rate of RBC unit transfusion was highest in the ICU (232.4 units/1000 patient-days; 95% confidence interval, 225.8-239.2; p < 0.0001 compared with all other locations).

CONCLUSION

Considerable variation was observed in estimated blood loss due to diagnostic phlebotomy across different services within one teaching hospital. Thi information is foundational for planning interventions to minimize estimated blood loss from phlebotomy.

摘要

背景

诊断检测的采血是最常见的医院操作之一,但尚未发表涵盖所有住院患者的血液抽取量的全院调查。目的是描述从加拿大三级保健中心出院的患者的每日诊断检测采血量,描述各服务地点的采血量的日分布,并描述各服务地点的血红蛋白(Hb)和输血的变化。

研究设计和方法

使用链接的出院摘要和实验室数据,获取 2012 年至 2014 年期间所有出院患者的数据。按服务和入院天数报告累计每日血液量和采血频率。为未输血和输血患者报告 Hb 和红细胞(RBC)输血率的变化。

结果

共纳入 59715 例患者。平均每日估计失血量从 8.5±6.5mL/天增加到 ICU 中的 27.2±20.0mL/天(p<0.001)。采血量在入院的第一天最高,此后下降(p<0.001)。在入院的第一周内未输血的个体,Hb 水平在 ICU 中下降幅度最大。在 ICU 中 RBC 单位输血率最高(232.4 单位/1000 患者-天;95%置信区间,225.8-239.2;与所有其他地点相比,p<0.0001)。

结论

在一家教学医院内,不同服务部门之间因诊断性采血而导致的估计失血量存在显著差异。该信息是规划干预措施以尽量减少采血引起的估计失血的基础。

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