Lucassen Eliane A, Boiten Jelis, Beishuizen Edith D
Haaglanden Medisch Centrum, afd. Interne Geneeskunde, Den Haag.
Contact: E.A. Lucassen (
Ned Tijdschr Geneeskd. 2019 Jul 5;163:D3939.
We present the case of a 58-year-old woman with multiple brain infarcts and livedo racemosa, a distinctive branched and irregular skin discoloration, on the trunk and limbs. Skin biopsy showed intimal proliferation with occlusion of a subcutaneous arteriole. We diagnosed Sneddon's syndrome, a rare neurocutaneous disorder likely caused by a noninflammatoryvasculopathy.
我们报告了一例58岁女性病例,该患者有多处脑梗死,且躯干和四肢出现了网状青斑,这是一种独特的分支状不规则皮肤变色。皮肤活检显示内膜增生,伴有一条皮下小动脉闭塞。我们诊断为斯内登综合征,这是一种罕见的神经皮肤疾病,可能由非炎性血管病变引起。