BCL-2家族的比较分析
A comparative analysis of BCL-2 family.
作者信息
Choudhury Shouhartha
机构信息
Department of Biotechnology, Assam University, Silchar-788011, Assam, India.
出版信息
Bioinformation. 2019 Apr 15;15(4):299-306. doi: 10.6026/97320630015299. eCollection 2019.
The BCL-2 family is conserved in evolution and shares a BCL-2 homology domain. It promotes and inhibits apoptosis. It is also known that apoptosis has a major role in effective cancer treatment. Therefore, it is of interest to document information related to the BCL-2 family of proteins for analysis by prediction tools. Hence, insights from a prediction based comparative functional analysis of 108 genes in this family are documented.
BCL-2家族在进化过程中保守，共享一个BCL-2同源结构域。它既能促进也能抑制细胞凋亡。众所周知，细胞凋亡在有效的癌症治疗中起着重要作用。因此，记录与BCL-2蛋白家族相关的信息以供预测工具分析很有意义。因此，本文记录了基于预测对该家族108个基因进行比较功能分析的见解。
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