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烧伤病房广泛耐药铜绿假单胞菌暴发:管理与解决方案

Extensively drug-resistant Pseudomonas Aeruginosa outbreak in a burn unit: management and solutions.

作者信息

Aguilera-Sáez J, Andreu-Solà V, Larrosa Escartín N, Rodríguez Garrido V, Armadans Gil L, Sánchez García J M, Campins M, Baena Caparrós J, Barret J P

机构信息

Vall d'Hebron University Hospital, Barcelona, Spain.

出版信息

Ann Burns Fire Disasters. 2019 Mar 31;32(1):47-55.

Abstract

Infections are still the main cause of mortality in burn patients. Multidrug resistant bacteria can cause outbreaks in critical care and burn units. We describe an outbreak of infection by extensively drug-resistant Pseudomonas aeruginosa in the Burn Unit of a University Hospital in Barcelona (Spain) between April and July 2016. A descriptive study of all cases, a bacterial colonization screening of all admitted patients and a microbiological environmental study were performed in order to detect a possible common focus. Contact isolation and cohortization of healthcare workers of all infected or colonized patients were applied. Environmental control measures were instituted for possible sources of infection. The outbreak was caused by a strain of P. aeruginosa only sensitive to colistin. Ten patients were infected or colonized and two of them died. The same strain was detected in several taps and drains in different rooms of the Unit. After applying control measures, changing faucets and drains, carrying out thermal disinfection of the hot water installation of the unit, disinfecting the rooms with ultraviolet radiation and placing antibacterial filtration devices in all the taps among other measures, an effective control of the outbreak was achieved.

摘要

感染仍然是烧伤患者死亡的主要原因。多重耐药菌可在重症监护病房和烧伤病房引发疫情。我们描述了2016年4月至7月间,西班牙巴塞罗那一家大学医院烧伤科发生的一起广泛耐药铜绿假单胞菌感染疫情。对所有病例进行了描述性研究,对所有入院患者进行了细菌定植筛查,并开展了微生物环境研究,以检测可能的共同感染源。对所有感染或定植患者的医护人员采取了接触隔离和分组措施。针对可能的感染源采取了环境控制措施。此次疫情由一株仅对黏菌素敏感的铜绿假单胞菌引起。10名患者被感染或定植,其中2人死亡。在该科室不同房间的多个水龙头和排水管道中检测到了同一菌株。采取控制措施,更换水龙头和排水管道,对科室的热水设施进行热消毒,用紫外线对房间进行消毒,并在所有水龙头处安装抗菌过滤装置等措施后,疫情得到了有效控制。

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