Brand Jordan, Tyagi Vineet, Rubin Lee
Yale New Haven Hospital New Haven, CT, USA.
Arthroplast Today. 2018 Oct 22;5(2):176-180. doi: 10.1016/j.artd.2018.09.006. eCollection 2019 Jun.
Osteogenesis imperfecta is a genetic disease resulting in abnormal collagen formation, with multiple clinical manifestations. Advancements in medical and surgical treatments have prolonged the life expectancy of these patients in recent decades. As a result, orthopedic surgeons are likely to be faced with the challenge of performing arthroplasty in these patients on a more frequent basis. Here, we describe a patient with osteogenesis imperfecta and subsequent severe osteoarthritis prompting primary total knee arthroplasty. This rare case presents an opportunity to explore special considerations unique to this patient population, including comorbid bone defects, the need for using extramedullary guides, careful alignment of prostheses to accommodate abnormalities in limb axes, and equipment utilization.
成骨不全症是一种导致胶原蛋白形成异常的遗传性疾病，有多种临床表现。近几十年来，医学和外科治疗的进步延长了这些患者的预期寿命。因此，骨科医生可能会更频繁地面临为这些患者进行关节置换术的挑战。在此，我们描述了一名患有成骨不全症并随后发展为严重骨关节炎而需要进行初次全膝关节置换术的患者。这个罕见的病例为探索该患者群体特有的特殊注意事项提供了机会，包括合并的骨缺损、使用髓外导向器的必要性、为适应肢体轴线异常而仔细调整假体的对线以及设备的使用。
