Uganda Paediatric Association, Kampala, Uganda.
Disease Control and Elimination Theme, Medical Research Council Unit, Banjul, The Gambia.
Paediatr Int Child Health. 2020 May;40(2):92-104. doi: 10.1080/20469047.2019.1638131. Epub 2019 Jul 10.
: Accurate documentation of neonatal morbidity and mortality is limited in many countries in sub-Saharan Africa. This project aimed to establish a surveillance system for neonatal conditions as an approach to improving the quality of neonatal care.: A systematic data capture and surveillance system was established at Jinja Regional Referral Hospital, Uganda using a standardised neonatal medical record form which collected detailed individual patient level data. Additionally, training and mentorship were conducted and basic equipment was provided.: A total of 4178 neonates were hospitalised from July 2014 to December 2016. Median (IQR) age on admission was one day (1-3) and 48.0% (1851/3859) were male. Median (IQR) duration of hospitalisation was 17 days (IQR 10-40) and the longest duration of hospitalisation was 47 days (IQR 41-58). The majority were referrals from government health facilities (54.4%, 2012/3699), though 30.6% (1123/3669) presented as self-referrals. Septicaemia (44.9%, 1962/4371), prematurity (21.0%, 917/4371) and birth asphyxia (19.1%, 833/4371) were the most common diagnoses. The overall mortality was 13.8% (577/4178) and the commonest causes of death included septicaemia (26.9%, 155/577), prematurity (24.3%, 140/577), birth asphyxia (21.0%, 121/577), hypothermia (9.9%, 57/577) and respiratory distress (8.0%, 46/577). The majority of deaths (51.5%, 297/577) occurred within the first 24 h of hospitalisation although a significant proportion of deaths also occurred after 7 days of hospitalisation (24.1%, 139/577). A modest decrease in mortality and improvement in clinical outcome were observed.: Improvement in neonatal data capture and quality of care was observed following establishment of an enhanced surveillance system, training and mentorship.: aOR: adjusted odds ratio; CHRP: Centre for Health research and Programmes; HC: health centre; HMIS: Health Management Information System; JRRH: Jinja Regional Referral Hospital; NMRF: neonatal medical record form; PMTCT: prevention of mother-to-child transmission of HIV; UPA: Uganda Paediatric Association.
在撒哈拉以南非洲的许多国家,新生儿发病率和死亡率的准确记录受到限制。本项目旨在建立新生儿疾病监测系统,以此作为提高新生儿护理质量的一种方法。
在乌干达金贾地区转诊医院建立了一个系统的数据采集和监测系统,使用标准化的新生儿病历表格,收集详细的个体患者数据。此外,还进行了培训和指导,并提供了基本设备。
2014 年 7 月至 2016 年 12 月期间,共有 4178 名新生儿住院。入院时的中位数(IQR)年龄为 1 天(1-3),48.0%(1851/3859)为男性。中位数(IQR)住院时间为 17 天(IQR 10-40),最长住院时间为 47 天(IQR 41-58)。大多数为政府卫生机构转诊(54.4%,2012/3699),但 30.6%(1123/3669)为自行转诊。败血症(44.9%,1962/4371)、早产(21.0%,917/4371)和出生窒息(19.1%,833/4371)是最常见的诊断。总死亡率为 13.8%(577/4178),最常见的死亡原因包括败血症(26.9%,155/577)、早产(24.3%,140/577)、出生窒息(21.0%,121/577)、体温过低(9.9%,57/577)和呼吸窘迫(8.0%,46/577)。大多数死亡(51.5%,297/577)发生在住院后 24 小时内,尽管相当一部分死亡也发生在住院后 7 天(24.1%,139/577)。死亡率略有下降,临床结局有所改善。
建立强化监测系统、培训和指导后,新生儿数据采集和护理质量得到改善。
aOR:调整后的优势比;CHRP:健康研究和计划中心;HC:卫生中心;HMIS:健康管理信息系统;JRRH:金贾地区转诊医院;NMRF:新生儿病历表;PMTCT:预防艾滋病毒母婴传播;UPA:乌干达儿科协会。