Hopper Andrew D, Jalal Mustafa, Munir Alia
Department of Gastroenterology, Royal Hallamshire Hospital, Sheffield, UK.
Department of Endocrinology, Royal Hallamshire Hospital, Sheffield, UK.
Frontline Gastroenterol. 2019 Jul;10(3):269-274. doi: 10.1136/flgastro-2018-101006. Epub 2018 Oct 9.
The incidence of pancreatic neuroendocrine tumours (PNET) is rising mainly due to the increased use of cross-sectional imaging. Although many PNETs are asymptomatic and non-functioning, the overall 5-year survival is still less than 50%. In this article, we review the advances in diagnosis, classification and staging of PNET that have evolved with the development of new cross-sectional imaging methods and biopsy techniques. With accurate classification, evidence-based, individualised prognostic outcomes and treatments are able to be given which are also discussed.
胰腺神经内分泌肿瘤（PNET）的发病率正在上升，主要原因是横断面成像技术的使用增加。尽管许多PNET无症状且无功能，但总体5年生存率仍低于50%。在本文中，我们回顾了随着新的横断面成像方法和活检技术的发展，PNET在诊断、分类和分期方面取得的进展。同时也讨论了通过准确分类如何给出基于证据的个体化预后结果和治疗方案。
