Heng Sharon, Hughes Brett, Hibbert Michael, Khasraw Mustafa, Lwin Zarnie
Monserrat North Lakes Day Hospital, North Lakes, QLD, Australia.
Royal Brisbane and Women's Hospital, Herston, QLD, Australia.
J Glob Oncol. 2019 Jul;5:1-10. doi: 10.1200/JGO.19.00029.
Travel for patients with cancer has become more achievable because of gains in quality of life and overall survival. The risk assessment of these patients is complex, and there is a paucity of data to which clinicians can refer. We present the challenges of traveling with cancer and a review of the literature.
A review using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines was performed. A search using the terms "cancer," "advanced cancer," "metastases," "brain edema," "lymphoedema," "pneumothorax," "pleural effusion," "pericardial effusion," pneumonitis," "hypoxia," "end-of-life," and "shunt," combined with "flying" and "air travel," was conducted. The PubMed and Cochrane databases were searched for English-language studies up to December 2018. Studies, case reports, or guidelines referring to travel in the context of adult patients with malignancies were included. A total of 745 published articles were identified; 16 studies were included. An inclusive approach to data extraction was used.
There were no specific criteria to deem a patient with cancer fit to travel. Neurologic, respiratory, and cardiac implications, and time from recent surgery or procedure need to be considered There was a lack of high-quality studies to inform decisions, but the British Thoracic Society and Aerospace Medical Association Medical Guidelines included recommendations for fitness to fly for patients with cancer.
In the absence of large prospective studies, individual fitness to travel should be assessed on a case-by-case basis, bearing in mind that maximizing a patient's ability to safely travel is an important goal for many individuals with cancer.
由于生活质量和总生存期的提高,癌症患者出行变得更可行。对这些患者的风险评估很复杂,临床医生可参考的数据很少。我们介绍了癌症患者出行面临的挑战并对文献进行综述。
按照系统评价和Meta分析的首选报告项目指南进行综述。使用“癌症”“晚期癌症”“转移”“脑水肿”“淋巴水肿”“气胸”“胸腔积液”“心包积液”“肺炎”“缺氧”“临终”和“分流”等术语,并结合“飞行”和“航空旅行”进行检索。在PubMed和Cochrane数据库中检索截至2018年12月的英文研究。纳入提及成年恶性肿瘤患者出行的研究、病例报告或指南。共识别出745篇已发表文章;纳入16项研究。采用包容性的数据提取方法。
没有判定癌症患者适合出行的具体标准。需要考虑神经、呼吸和心脏方面的影响,以及距近期手术或治疗的时间。缺乏高质量研究为决策提供依据,但英国胸科学会和航空航天医学协会的医学指南包含了癌症患者飞行适宜性的建议。
在缺乏大型前瞻性研究的情况下,应逐案评估个人的出行适宜性,要记住,对许多癌症患者而言,最大限度提高其安全出行能力是一个重要目标。