Alvim André Luiz Silva, Couto Bráulio Roberto Gonçalves Marinho, Gazzinelli Andrea
Universidade Federal de Minas Gerais, Programa de Pós-Graduação em Enfermagem, Belo Horizonte, MG, Brazil.
Centro Universitário de Belo Horizonte - UniBH, Departamento de Engenharia e Estatística, Belo Horizonte, MG, Brazil.
Rev Esc Enferm USP. 2019 Jul 4;53:e03474. doi: 10.1590/S1980-220X2018001903474.
To study the epidemiological profile of Healthcare-associated Infections caused by Enterobacteria which carry the Klebsiella pneumoniae Carbapenemase gene (blaKPC) in the hospital environment.
A descriptive study was conducted in a private hospital in Belo Horizonte, MG, Brazil, which included all patients with infections caused by Enterobacteriaceae which carry the Klebsiella pneumoniae Carbapenemase gene. The data were collected by the Automated System of Hospital Infection Control and analyzed by descriptive statistics by the Epi Info 7 program.
Eighty-two (82) patients participated in the study. Klebsiella pneumoniae was the most frequent species (68%) isolated in blood (30%), bronchoalveolar lavage (22%) and urine (18%), while catheter-associated bloodstream infection (30%) predominated regarding topography. A case fatality rate of 62% is highlighted in evaluating the outcome.
The resistance genes spread rapidly, limiting the antimicrobial options for treating infectious diseases. The epidemiological profile of Healthcare-Associated Infections found in this study can be prevented by prevention and infection control programs.
研究医院环境中携带肺炎克雷伯菌碳青霉烯酶基因（blaKPC）的肠杆菌科细菌引起的医疗保健相关感染的流行病学特征。
在巴西米纳斯吉拉斯州贝洛奥里藏特的一家私立医院进行了一项描述性研究，纳入所有由携带肺炎克雷伯菌碳青霉烯酶基因的肠杆菌科细菌引起感染的患者。数据通过医院感染控制自动化系统收集，并由Epi Info 7程序进行描述性统计分析。
82名患者参与了该研究。肺炎克雷伯菌是血液（30%）、支气管肺泡灌洗（22%）和尿液（18%）中分离出的最常见菌种（68%），而就感染部位而言，导管相关血流感染占主导（30%）。评估结果时突出显示病死率为62%。
耐药基因迅速传播，限制了治疗传染病的抗菌药物选择。本研究中发现的医疗保健相关感染的流行病学特征可通过预防和感染控制计划加以预防。
