Department of Chemistry, Isfahan University of Technology, Isfahan, 84156-83111, Iran.
Mikrochim Acta. 2019 Jul 10;186(8):524. doi: 10.1007/s00604-019-3641-0.
Molecularly imprinted-electrospun nanofibers based on the use of poly(vinyl alcohol) were fabricated and used as a new sorbent for solid-phase microextraction of chlorpyrifos. The molecularly imprinted nanofibers were prepared by electrospinning and direct molecular imprinting of polymeric nanofibers. Poly(vinyl alcohol) was used as the functional and electrospun polymer. Chlorpyrifos was used as a template molecule, and glutaraldehyde as the cross-linker. Detection was performed by ion mobility spectrometry equipped with a secondary electrospray ionization source. The molecularly imprinted fiber has a selectivity and extraction efficiency better than the fiber fabricated using the conventional method of encapsulating MIP particles in electrospun nanofibers. Parameters affecting the extraction efficiency such as ionic strength, stirring rate, extraction time, and temperature were evaluated. The dynamic range of the method was in the range of 0.5-200 μg L with the limit of detection of 0.1 μg L. The intra- and inter-day relative standard deviations of the method were 4 and 9%, respectively. The fiber-to-fiber reproducibility for three different fibers is 5%. The spiking recoveries from spiked apple, cucumber, and water samples were in the range of 82-112%. Graphical abstract Molecularly imprinted-electrospun nanofibers were fabricated based on the direct molecular imprinting technique and used as a new SPME fiber coating for selective extraction of chlorpyrifos from fruits and water samples prior its determination by secondary electrospray ionization-ion mobility spectrometry.
基于使用聚乙烯醇的分子印迹-静电纺纳米纤维被制备并用作固相微萃取中氯吡磷的新型吸附剂。分子印迹纳米纤维是通过静电纺丝和聚合物纳米纤维的直接分子印迹制备的。聚乙烯醇被用作功能和静电纺丝聚合物。氯吡磷被用作模板分子，戊二醛用作交联剂。检测是通过配备二次电喷雾电离源的离子淌度谱法进行的。与使用将 MIP 颗粒封装在静电纺纳米纤维中的常规方法制造的纤维相比，分子印迹纤维具有更好的选择性和萃取效率。评估了影响萃取效率的参数，例如离子强度、搅拌速率、萃取时间和温度。该方法的动态范围在 0.5-200μg/L 范围内，检出限为 0.1μg/L。该方法的日内和日间相对标准偏差分别为 4%和 9%。三根不同纤维的纤维间重现性为 5%。从苹果、黄瓜和水样中加标回收的回收率在 82-112%范围内。
