Department of Pathology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, L-113, Portland, OR, 97239, USA.
Head Neck Pathol. 2020 Jun;14(2):550-553. doi: 10.1007/s12105-019-01052-y. Epub 2019 Jul 10.
Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is an uncommon lymphoma that accounts for 3-8% of all Hodgkin lymphomas. NLPHL typically presents as early stage disease with localized peripheral lymphadenopathy. Involvement of extranodal sites at the time of presentation occurs in 6% of cases and most commonly involves the spleen, liver, bone marrow, and Waldeyer ring. Primary extranodal NLPHL is exceedingly rare. We describe the first reported case involving the thyroid and review the six other previously described cases of primary extranodal NLPHL.
结节性淋巴细胞为主型霍奇金淋巴瘤（NLPHL）是一种不常见的淋巴瘤，占所有霍奇金淋巴瘤的 3-8%。NLPHL 通常表现为早期疾病，伴有局部外周淋巴结病。6%的病例在发病时会出现结外部位受累，最常见的受累部位是脾脏、肝脏、骨髓和咽淋巴环。原发性结外 NLPHL 极为罕见。我们描述了首例涉及甲状腺的病例，并回顾了之前描述的其他 6 例原发性结外 NLPHL 病例。
