Gupta Parul, Mishra Rohini, Gupta Manoj, Choudhury Partha Sarthi
Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India.
Indian J Nucl Med. 2019 Jul-Sep;34(3):213-215. doi: 10.4103/ijnm.IJNM_50_19.
Prostate cancer (PCa) is the second most frequent malignancy in men. Most common sites of disease involvement other than the prostate gland include abdominopelvic lymph nodes and the skeleton. The detection of nodal metastases is of utmost importance to determine prognosis and choice of treatment in patients with PCa. Conventional imaging focuses on morphologic information and takes size criteria for decision-making. Early detection of metastases is further relevant in terms of prognosis and therapy management. Molecular imaging of PCa with Ga-68 prostate-specific membrane antigen (PSMA) positron emission tomography-computed tomography (PET-CT) has recently received significant attention and frequently used with a signature to PCa-specific remark. We presented the case of a 69-year-old male presenting with biochemical recurrence after undergoing surgery and in remission for about a year, where Ga-68 PSMA PET-CT identified additional sites of disease apart from the expected regional bed.
前列腺癌（PCa）是男性中第二常见的恶性肿瘤。除前列腺外，疾病最常累及的部位包括腹盆腔淋巴结和骨骼。检测淋巴结转移对于确定前列腺癌患者的预后和治疗选择至关重要。传统成像侧重于形态学信息，并以大小标准进行决策。转移灶的早期检测在预后和治疗管理方面也具有重要意义。采用镓-68前列腺特异性膜抗原（PSMA）正电子发射断层扫描-计算机断层扫描（PET-CT）对前列腺癌进行分子成像最近受到了广泛关注，并常被用于前列腺癌的特异性诊断。我们报告了一例69岁男性患者的病例，该患者术后出现生化复发并缓解约一年，镓-68 PSMA PET-CT检查发现除预期的局部区域外还有其他疾病部位。
