体外循环期间微循环的监测与优化。
Monitoring and optimization of the microcirculation during CPB.
作者信息
Murkin John M
机构信息
Department of Anesthesia & Perioperative Medicine, London Health Sciences Centre, University Hospital, London, ON, Canada.
出版信息
J Thorac Dis. 2019 Jun;11(Suppl 10):S1489-S1491. doi: 10.21037/jtd.2019.02.100.
Abstract
In this review the impact of cardiopulmonary bypass (CPB) on the microcirculation is discussed. The impact of conventional non-pulsatile perfusion is contrasted with the microcirculatory impact of pulsatile CPB which is associated with better preservation of microcirculatory function. Evidence that alterations in microcirculatory function that persist following cardiac surgery are associated with adverse clinical outcomes is reviewed. Recent studies using novel techniques employing near infrared reflectance spectroscopy (NIRS) and sublingual microscopy to explore alterations in microcirculatory function during CPB are reviewed and the implications of these observations for studies investigating minimally invasive extracorporeal circulation (MiECC) are discussed.
摘要
在本综述中，讨论了体外循环（CPB）对微循环的影响。将传统非搏动性灌注的影响与搏动性CPB的微循环影响进行了对比，搏动性CPB与更好地保留微循环功能相关。综述了心脏手术后持续存在的微循环功能改变与不良临床结局相关的证据。回顾了最近使用近红外反射光谱（NIRS）和舌下显微镜等新技术来探索CPB期间微循环功能改变的研究，并讨论了这些观察结果对研究微创体外循环（MiECC）的意义。
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