Department of Community and Health Values Integration, Centura Health, 91000 E. Mineral Circle, Centennial, CO, USA.
Department of Population Health, School of Medicine and Health Sciences, University of North Dakota, 1301 North Columbia Road, Grand Forks, ND, USA.
Int Health. 2019 Nov 13;11(6):580-588. doi: 10.1093/inthealth/ihz027.
The purpose of the current study was to investigate the association between obesity and self-reported current depression (SRCD) in a population-based sample of adult Brazilian cancer survivors.
The sample for this study (N=930) was based on the 2013 Brazilian National Health Survey. SRCD was assessed using the 8-item Patient Health Questionnaire (PHQ-8). Obesity was defined as a body mass index ≥30 kg/m2. Multivariable weighted logistic regression models were conducted to investigate the association between obesity and SRCD among Brazilian adult cancer survivors.
The weighted prevalence of obesity and SRCD among adult cancer survivors was 26.4% (95% confidence interval [CI] 22.5 to 30.3%) and 13.7% (95% CI 10.4 to 17.1%), respectively. Overall there was no significant weighted and adjusted association between obesity and SRCD among cancer survivors (adjusted odds ratio [AOR] 0.99 [95% CI 0.56 to 1.73]). Nevertheless, among cancer survivors of working age (18-59 y), this association was significant (AOR 2.19 [95% CI 1.28 to 3.73]) and therefore obesity is significantly associated with a 119% increase in the odds of SRCD among Brazilian adult cancer survivors of working age.
Since both obesity and depression may lead to worse health and quality of life outcomes in this young and middle-aged population, further investigations are needed in order to establish the causality and directionality of this association.
本研究的目的是在巴西癌症幸存者的人群中，调查肥胖与自我报告的当前抑郁（SRCD）之间的关联。
本研究的样本（N=930）基于 2013 年巴西国家健康调查。使用 8 项患者健康问卷（PHQ-8）评估 SRCD。肥胖定义为体质指数≥30kg/m2。采用多变量加权逻辑回归模型，调查巴西成年癌症幸存者中肥胖与 SRCD 之间的关系。
成年癌症幸存者中肥胖和 SRCD 的加权患病率分别为 26.4%（95%置信区间[CI] 22.5 至 30.3%）和 13.7%（95%CI 10.4 至 17.1%）。总体而言，癌症幸存者中肥胖与 SRCD 之间无显著的加权和调整关联（调整后的优势比[AOR]0.99[95%CI 0.56 至 1.73]）。然而，在 18-59 岁的癌症幸存者中，这种关联具有统计学意义（AOR 2.19[95%CI 1.28 至 3.73]），因此肥胖与巴西成年癌症幸存者中 SRCD 的几率增加 119%相关。
由于肥胖和抑郁都会导致这一年轻和中年人群的健康和生活质量下降，因此需要进一步调查以确定这种关联的因果关系和方向性。
