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控制营养状况(CONUT)评分可预测脑卒中患者 3 个月全因死亡率。

Controlling Nutritional Status (CONUT) Score as a Predictor of All-Cause Mortality at 3 Months in Stroke Patients.

机构信息

1 Department of Nursing, Nursing and Occupational Therapy College, University of Extremadura, Cáceres, Spain.

2 Stroke Unit, Department of Neurology, Hospital San Pedro de Alcantara, Cáceres, Spain.

出版信息

Biol Res Nurs. 2019 Oct;21(5):564-570. doi: 10.1177/1099800419860253. Epub 2019 Jul 11.

Abstract

UNLABELLED

Malnutrition is frequently observed in patients after stroke and is associated with poor outcomes. Patients at risk of malnutrition may be identified with several nutrition screening tools, but no nutritional screening tool has been validated for use with stroke patients. The aim of this study was to explore the ability of the Controlling Nutritional Status (CONUT) score to predict 3-month mortality in stroke patients.

METHOD

Patients were recruited from consecutive admissions at a hyperacute stroke unit and were screened for risk of malnutrition (light, moderate, or severe) using CONUT scores. At the next visit, 3-month outcomes were obtained.

RESULTS

Of the 164 recruited patients, 51.2% were male. Mean patient age was 77.7 ( = 7.0) years, and 85.8% of patients had an ischemic stroke. There was a significant difference in the survival rate ( < .001) at 3 months between patients with moderate risk for malnourishment compared to the other patients. The multivariate regression Cox model showed that moderate risk of malnourishment, according to the CONUT score, increased the risk for death at 3 months (hazard ratio = 1.086; 95% CI [1.057, 8.305]; < .039).

CONCLUSION

The CONUT score has predictive validity for all-cause mortality in stroke patients after 3 months, both in hospital and after discharge. Further prospective multicenter studies with larger samples are needed to clarify the usefulness of the CONUT score in the prognosis of all-cause mortality in stroke patients.

摘要

目的

探讨控制营养状况(CONUT)评分预测卒中患者 3 个月死亡率的能力。

方法

连续纳入急性卒中单元的患者,采用 CONUT 评分筛查营养不良风险(轻度、中度或重度)。下一次就诊时,获得 3 个月的结局。

结果

共纳入 164 例患者,51.2%为男性。患者平均年龄为 77.7(=7.0)岁,85.8%为缺血性卒中。根据 CONUT 评分,中度营养不良风险患者的 3 个月生存率存在显著差异( <.001)。多变量回归 Cox 模型显示,根据 CONUT 评分,中度营养不良风险增加了 3 个月时死亡的风险(危险比=1.086;95%CI[1.057,8.305]; <.039)。

结论

CONUT 评分对卒中患者 3 个月后全因死亡率具有预测价值,包括住院期间和出院后。需要进一步进行前瞻性多中心研究,以阐明 CONUT 评分在预测卒中患者全因死亡率方面的作用。

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