Ophthalmology Department, Ankara Ataturk Training and Research Hospital, Ankara, Turkey.
Radiology Department, Ankara Ataturk Training and Research Hospital, Ankara, Turkey.
Orbit. 2020 Jun;39(3):160-164. doi: 10.1080/01676830.2019.1639770. Epub 2019 Jul 11.
: To evaluate the affected extraocular muscles (EOMs) of patients with Graves' ophthalmopathy (GO) using real-time ultrasound elastography (UE) and to compare these results with those of healthy subjects.: This prospective, comparative case series included 70 eyes of 35 patients with moderate-to-severe GO with type 2 orbitopathy (myogenic variant) according to their computed tomography (CT) scans. Forty-six eyes of 23 healthy subjects were evaluated as the control group. The strain ratio of orbital fat to medial rectus was calculated as the ratio of the medial rectus to orbital fat tissue, and the strain ratio of orbital fat to lateral rectus was calculated as the ratio of lateral rectus to orbital fat tissue.: The strain ratio of orbital fat to medial rectus was 3.03 ± 1.25 (range: 1.05-5.07) in the GO group, and 0.54 ± 0.20 (range: 0.14-1.08) in the control group ( = .0001). The strain ratio of orbital fat to lateral rectus was 0.97 ± 0.29 (range: 0.56-1.55) in the GO group, and 0.63 ± 0.23 (range: 0.18-1.09) in the control group ( = .0001).: By using real-time UE, we found the medial and the lateral recti of GO patients to be stiffer compared to those of healthy subjects.
评估格雷夫斯眼病（GO）患者的受影响眼外肌（EOM）使用实时超声弹性成像（UE），并将这些结果与健康受试者进行比较。
这项前瞻性、对照病例系列研究纳入了 35 例中重度 GO 患者的 70 只眼，这些患者根据计算机断层扫描（CT）扫描均为 2 型眼眶病（肌源性变异）。23 例健康受试者的 46 只眼被评估为对照组。眼眶脂肪与内直肌的应变比计算为内直肌与眼眶脂肪组织的比值，眼眶脂肪与外直肌的应变比计算为外直肌与眼眶脂肪组织的比值。
GO 组眼眶脂肪与内直肌的应变比为 3.03 ± 1.25（范围：1.05-5.07），对照组为 0.54 ± 0.20（范围：0.14-1.08）（ = 0.0001）。GO 组眼眶脂肪与外直肌的应变比为 0.97 ± 0.29（范围：0.56-1.55），对照组为 0.63 ± 0.23（范围：0.18-1.09）（ = 0.0001）。
通过使用实时 UE，我们发现 GO 患者的内直肌和外直肌比健康受试者更硬。
