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低级别卵巢浆液性癌——一项临床形态学研究

Low Grade Ovarian Serous Carcinoma - A Clinical-Morphologic Study.

作者信息

Dochiț C, Stepan A E, Mărgăritescu C, Ciurea R, Simionescu C E

机构信息

PhD Student, University of Medicine and Pharmacy of Craiova, Romania.

Department of Pathology, University of Medicine and Pharmacy of Craiova, Romania.

出版信息

Curr Health Sci J. 2019 Jan-Mar;45(1):42-46. doi: 10.12865/CHSJ.45.01.05. Epub 2019 Mar 31.

DOI:10.12865/CHSJ.45.01.05
PMID:31297261
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6592674/
Abstract

Low grade ovarian serous carcinomas (LGSC) are rare tumors, representing only a small part of all ovarian carcinomas. The study included six LGSC cases for which we followed the clinical-epidemiological and morphological parameters depending on the tumoral stages. The tumors corresponded to stage I in four cases, in one case to stage II and in another case to stage III. The majority of the analyzed histopathological parameters were present in all tumoral stages. The accuracy of the diagnostic and the correct staging of the LGSC affected patients is very important, because the grade and stage of the serous ovarian tumors impose the therapy and the prognosis.

摘要

低级别卵巢浆液性癌(LGSC)是罕见肿瘤,仅占所有卵巢癌的一小部分。该研究纳入了6例LGSC病例,我们根据肿瘤分期跟踪了临床流行病学和形态学参数。4例肿瘤为I期,1例为II期,另1例为III期。大多数分析的组织病理学参数在所有肿瘤分期中均存在。准确诊断和正确分期受LGSC影响的患者非常重要,因为浆液性卵巢肿瘤的分级和分期决定了治疗方案和预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a64/6592674/149ab6f87506/CHSJ-45-01-42-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a64/6592674/747e88099ffc/CHSJ-45-01-42-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a64/6592674/1c630d03af0d/CHSJ-45-01-42-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a64/6592674/a836c5416417/CHSJ-45-01-42-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a64/6592674/149ab6f87506/CHSJ-45-01-42-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a64/6592674/747e88099ffc/CHSJ-45-01-42-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a64/6592674/1c630d03af0d/CHSJ-45-01-42-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a64/6592674/a836c5416417/CHSJ-45-01-42-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a64/6592674/149ab6f87506/CHSJ-45-01-42-fig4.jpg

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本文引用的文献

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Am J Surg Pathol. 2016 Sep;40(9):1165-76. doi: 10.1097/PAS.0000000000000693.
2
Low-grade serous carcinoma of the ovary or peritoneum.卵巢或腹膜低级别浆液性癌。
Ann Oncol. 2016 Apr;27 Suppl 1:i45-i49. doi: 10.1093/annonc/mdw085.
3
Ovarian Low-grade Serous Carcinoma: A Clinicopathologic Study of 33 Cases With Primary Surgery Performed at a Single Institution.
卵巢低级别浆液性癌:对在单一机构进行初次手术的33例病例的临床病理研究
Am J Surg Pathol. 2016 May;40(5):627-35. doi: 10.1097/PAS.0000000000000615.
4
Impact of Age and Primary Disease Site on Outcome in Women With Low-Grade Serous Carcinoma of the Ovary or Peritoneum: Results of a Large Single-Institution Registry of a Rare Tumor.年龄和原发疾病部位对卵巢或腹膜低级别浆液性癌女性患者预后的影响:一项大型单机构罕见肿瘤登记研究的结果
J Clin Oncol. 2015 Aug 20;33(24):2675-82. doi: 10.1200/JCO.2015.61.0873. Epub 2015 Jul 20.
5
Survival in women with grade 1 serous ovarian carcinoma.1 级浆液性卵巢癌患者的生存情况。
Obstet Gynecol. 2013 Aug;122(2 Pt 1):225-232. doi: 10.1097/AOG.0b013e31829ce7ec.
6
Morphological and molecular basis of ovarian serous carcinoma.卵巢浆液性癌的形态学和分子基础
J Biomed Res. 2010 Jul;24(4):257-63. doi: 10.1016/S1674-8301(10)60036-X.
7
Ovarian serous tumors of low malignant potential with nodal low-grade serous carcinoma.低恶性潜能的卵巢浆液性肿瘤伴淋巴结低级别浆液性癌。
Am J Surg Pathol. 2012 Jul;36(7):955-63. doi: 10.1097/PAS.0b013e31825793e1.
8
Ovarian low-grade serous carcinoma involving the cervix mimicking a cervical primary.宫颈低级别浆液性卵巢癌累及宫颈,类似于宫颈原发性肿瘤。
Int J Gynecol Pathol. 2011 Nov;30(6):613-9. doi: 10.1097/PGP.0b013e318217137e.
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Patterns of low-grade serous carcinoma with emphasis on the nonepithelial-lined spaces pattern of invasion and the disorganized orphan papillae.低级别浆液性癌的模式,重点是无上皮衬里的腔隙浸润模式和紊乱的孤立乳头。
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