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一种用于在解剖结构改变或异常情况下的Descemet膜剥除自动内皮角膜移植术(DSAEK)的改良手术技术。

A modified surgical technique for Descemet's stripping automated endothelial keratoplasty (DSAEK) in altered or abnormal anatomy.

作者信息

Koo Ellen H

机构信息

Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Bascom Palmer Eye Institute, 900 NW 17th St, Miami, FL 33136, FL, USA.

出版信息

Am J Ophthalmol Case Rep. 2019 Jun 13;15:100497. doi: 10.1016/j.ajoc.2019.100497. eCollection 2019 Sep.

DOI:10.1016/j.ajoc.2019.100497
PMID:31297466
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6598032/
Abstract

PURPOSE

This paper describes a modified technique for the Descemet's Stripping Automated Endothelial Keratopasty (DSAEK) surgery in eyes with abnormal or altered anatomy. Certain anatomic abnormalities increase the level of surgical complexity, and lead to increased risk of donor lenticule detachment. These challenges include aniridia, abnormal iris, aphakia and hypotony from previous vitrectomy.

OBSERVATIONS

The Sheets glide was trimmed to 4mm in width and inserted into the clear-corneal wound. The "needle-push"/Fichman glide technique was used to insert the DSAEK donor graft. The modification of the technique involves maintaining the Sheets glide in the eye for the duration of the intraoperative air bubble. After confirming desired orientation of the graft, air was injected into the anterior chamber, creating a large air bubble between the graft and the Sheets glide. After 10 minutes, the Sheets glide was removed, and the main wound was closed.

CONCLUSIONS AND IMPORTANCE

This technique overcomes the challenges of posterior air bubble migration and posterior dislocation of the donor lenticule in eyes with altered anatomy.

摘要

目的

本文描述了一种用于解剖结构异常或改变的眼睛的改良Descemet膜剥脱自动内皮角膜移植术(DSAEK)技术。某些解剖异常会增加手术复杂性,并导致供体晶状体瓣脱离的风险增加。这些挑战包括无虹膜、虹膜异常、无晶状体以及既往玻璃体切除术后的低眼压。

观察结果

将Sheets滑瓣修剪至4毫米宽,并插入透明角膜伤口。采用“针推”/菲克曼滑瓣技术插入DSAEK供体移植物。该技术的改良包括在术中气泡持续期间将Sheets滑瓣保留在眼内。在确认移植物的理想方向后,向前房注入空气,在移植物和Sheets滑瓣之间形成一个大气泡。10分钟后,取出Sheets滑瓣,并关闭主伤口。

结论与意义

该技术克服了解剖结构改变的眼睛中后气泡迁移和供体晶状体瓣后脱位的挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da7f/6598032/6b79779f07d1/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da7f/6598032/6b79779f07d1/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da7f/6598032/6b79779f07d1/gr1.jpg

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本文引用的文献

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Endothelial Cell Loss After Needle-Push Insertion Descemet Stripping Endothelial Keratoplasty (DSEK).针推式插入后弹力层剥离内皮角膜移植术(DSEK)后的内皮细胞丢失
Cornea. 2016 Jun;35(6):e16-7. doi: 10.1097/ICO.0000000000000835.
2
Keratoplasty in the United States: A 10-Year Review from 2005 through 2014.美国的角膜移植术:2005 年至 2014 年的 10 年回顾。
Ophthalmology. 2015 Dec;122(12):2432-42. doi: 10.1016/j.ophtha.2015.08.017. Epub 2015 Sep 19.
3
Factors affecting DSAEK graft lenticle adhesion: an in vitro experimental study.
影响 DSAEK 移植物小体黏附的因素:一项体外实验研究。
Cornea. 2014 Jun;33(6):551-4. doi: 10.1097/ICO.0000000000000125.
4
Dislocation of the donor graft to the posterior segment in descemet stripping automated endothelial keratoplasty.撕囊自动化角膜内皮移植术中供体移植物后段脱位。
Am J Ophthalmol. 2012 Apr;153(4):638-42, 642.e1-2. doi: 10.1016/j.ajo.2011.09.006. Epub 2011 Nov 20.
5
Modified surgical technique for improving donor adherence in DSAEK in the aphakic vitrectomized eye.改良手术技术提高无晶状体玻璃体切除眼中 DSAEK 中供体的贴合度。
Cornea. 2012 Apr;31(4):462-4. doi: 10.1097/ICO.0b013e31821c9bd1.
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[Complications after endothelial keratoplasty: three years of experience].[内皮角膜移植术后并发症:三年经验]
Arch Soc Esp Oftalmol. 2011 Jun;86(6):180-6. doi: 10.1016/j.oftal.2010.12.013. Epub 2011 Apr 20.
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Transcorneal suture fixation of posterior lamellar grafts in eyes with minimal or absent iris-lens diaphragm.经角膜缝线固定后板层移植物于最小或无虹膜晶状体膈的眼睛中。
Am J Ophthalmol. 2011 Mar;151(3):460-4.e2. doi: 10.1016/j.ajo.2010.08.043. Epub 2011 Jan 12.
8
Simple technique for graft insertion in Descemet-stripping (automated) endothelial keratoplasty using a 30-gauge needle.使用30号针头在Descemet膜剥除(自动)内皮角膜移植术中进行植片植入的简单技术。
J Cataract Refract Surg. 2009 Apr;35(4):625-8. doi: 10.1016/j.jcrs.2008.10.059.
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Complications of Descemet's stripping with automated endothelial keratoplasty: survey of 118 eyes at One Institute.自动角膜内皮移植术行后弹力层剥除的并发症:一所机构118只眼的调查
Ophthalmology. 2008 Sep;115(9):1517-24. doi: 10.1016/j.ophtha.2008.01.024. Epub 2008 Apr 18.
10
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Cornea. 2007 Oct;26(9):1123-6. doi: 10.1097/ICO.0b013e318124a443.