Seaver Autism Center for Research and Treatment, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY, 10029, USA.
Department of Psychology, University of Massachusetts Boston, 100 Morrissey Blvd, Boston, MA, 02125, USA.
J Autism Dev Disord. 2020 Sep;50(9):3263-3275. doi: 10.1007/s10803-019-04138-2.
Determining diagnostic stability of ASD, as well stability of functioning in early childhood, is relevant to prevalence, best practices for communicating early ASD diagnoses to caregivers, families' experiences, and developmental trajectories. Generalizability of findings from prior research has been limited by small and homogenous samples, short follow-up time intervals, and inconsistent diagnostic procedures. This report presents follow-up evaluations of 60 children (86.7% male, mean age: 51.3 months) with diverse backgrounds (79.7% racial/ethnic minorities) who received initial ASD diagnoses before 36 months of age (mean age: 27 months). Fifty-three children (88.3%) met diagnostic criteria for ASD at follow-up, a proportion consistent with previous studies. On average, children demonstrated significant cognitive gains and ASD symptom improvement. Clinical implications of findings are discussed.
确定 ASD 的诊断稳定性,以及幼儿期功能的稳定性,与患病率、向照顾者传达早期 ASD 诊断的最佳实践、家庭体验和发展轨迹有关。先前研究的发现的普遍性受到小而同质的样本、随访时间间隔短以及不一致的诊断程序的限制。本报告介绍了对 60 名儿童(86.7%为男性,平均年龄:51.3 个月)的随访评估,这些儿童来自不同背景(79.7%为少数族裔),他们在 36 个月之前(平均年龄:27 个月)接受了 ASD 的初步诊断。53 名儿童(88.3%)在随访时符合 ASD 的诊断标准,这一比例与先前的研究一致。平均而言,儿童表现出显著的认知进步和 ASD 症状改善。讨论了研究结果的临床意义。