Department of Epidemiology and Biostatistics, Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand; Integrated Epilepsy Research Group, Khon Kaen University, Khon Kaen, Thailand.
Department of Epidemiology and Biostatistics, Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand.
Epilepsy Behav. 2019 Dec;101(Pt B):106372. doi: 10.1016/j.yebeh.2019.06.016. Epub 2019 Jul 10.
Status epilepticus (SE) is a neurological disorder that affects to the high mortality risk. Several studies reported predictors of mortality in SE; actual causes of death in hospital and out of hospital are limited. This study aimed to describe the case fatality and the causes of death in patients with SE.
This was a descriptive study using the data collected in the national data of the Universal Coverage Scheme in Thailand during the fiscal year 2005 to 2015. Patients who admitted to hospitals and diagnosed as SE were included. The vital status of patients with SE was linked with the Ministry of the Interior and was classified into three phases: in-hospital, short-term, and long-term.
Among 24,802 patients with SE, 1861 (7.5%) died in hospital, 1910 (7.7%) died within 30 days after hospital discharge, and 4906 (19.8%) died after 30 days. In-hospital death, SE complications (45.9%), seizure (19.6%), and comorbidities (15.4%) were the three common causes of death. While the common causes in short-term and long-term mortality were SE complications (27.7% and 31.0%), comorbidities (28.1% and 26.7%), and other causes (22.4% and 21.9%).
Status epilepticus complications and comorbidities were the common cause of death in patients with SE for all of three periods. This article is part of the Special Issue "Proceedings of the 7th London-Innsbruck Colloquium on Status Epilepticus and Acute Seizures".
癫痫持续状态（SE）是一种影响高死亡率的神经系统疾病。几项研究报告了 SE 的死亡率预测因素；但在医院内和医院外的实际死亡原因有限。本研究旨在描述 SE 患者的病死率和死亡原因。
这是一项描述性研究，使用了 2005 年至 2015 年泰国全民覆盖计划的国家数据中收集的数据。纳入了因 SE 入院并被诊断为 SE 的患者。SE 患者的生存状况与内政部相关联，并分为三个阶段：住院期间、短期和长期。
在 24802 例 SE 患者中，1861 例（7.5%）在医院死亡，1910 例（7.7%）在出院后 30 天内死亡，4906 例（19.8%）在 30 天后死亡。在医院内死亡的原因中，SE 并发症（45.9%）、癫痫发作（19.6%）和合并症（15.4%）是死亡的三个常见原因。而在短期和长期死亡的常见原因中，SE 并发症（27.7%和 31.0%）、合并症（28.1%和 26.7%）和其他原因（22.4%和 21.9%）。
SE 并发症和合并症是所有三个时期 SE 患者死亡的常见原因。本文是“第七届伦敦-因斯布鲁克癫痫持续状态和急性发作研讨会特刊”的一部分。
