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多模式局部阿片类药物处方干预在慢性非癌性疼痛管理中的效果。

Multimodal Local Opioid Prescribing Intervention Outcomes in Chronic Noncancer Pain Management.

机构信息

From Aurora Health Care, Department of Family Medicine, Aurora St. Luke's Medical Center, Milwaukee, WI (NPA, FK, DJB); Aurora Health Care, Department of Internal Medicine, Aurora St. Luke's Medical Center, Milwaukee, WI (NPA); Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, Madison (FK, JJFK, DJB); Aurora Health Care, Aurora UW Medical Group and Center for Urban Population Health, Aurora Sinai Medical Center, Milwaukee, WI (JJFK, DJB).

出版信息

J Am Board Fam Med. 2019 Jul-Aug;32(4):559-566. doi: 10.3122/jabfm.2019.04.180296.

Abstract

BACKGROUND

Opioid misuse in the United States has made it challenging for physicians to treat chronic noncancer pain (CNCP). We implemented an educational program aimed at promoting safe opioid prescribing practices in hopes of increasing the level of appropriateness associated with prescribing opioids for CNCP.

METHODS

We conducted a quality-improvement study with a retrospective chart review of adult patients who were prescribed opioids for CNCP for at least 90 consecutive days at 2 academic primary care clinics. Patients were reviewed at baseline (July 2014-May 2015) and after initial interventions (January 2016-June 2016; ie, following multimodal educational activities on appropriate opioid prescription implemented from June 2015-December 2015). An opioid appropriateness score was calculated based on documentation of 9 items. Categorical variables were analyzed with Fisher exact tests and continuous variables by 2-sample tests and regression analysis. Binary logistic regression was used for multivariable modeling. Mann-Whitney test was used to compare appropriateness scores before and after intervention.

RESULTS

A total of 177 and 96 patients were evaluated at baseline and postintervention, respectively. Patient demographic characteristics were not statistically different. Overall, postintervention level of appropriateness was significantly different from preintervention ( < .0001), with means increasing from 5.54 preintervention to 6.29 postintervention. Both clinics had significant improvement from baseline (both values <.003).

CONCLUSIONS

Clinician education on best practices while treating CNCP is associated with an increase in the level of opioid use appropriateness.

摘要

背景

在美国,阿片类药物滥用使得医生治疗慢性非癌性疼痛(CNCP)变得具有挑战性。我们实施了一项教育计划,旨在促进安全的阿片类药物处方实践,希望提高与 CNCP 开具阿片类药物相关的适当性水平。

方法

我们进行了一项质量改进研究,对在 2 家学术初级保健诊所至少连续 90 天开具阿片类药物治疗 CNCP 的成年患者进行了回顾性图表审查。患者在基线(2014 年 7 月至 2015 年 5 月)和初步干预后(2016 年 1 月至 6 月;即,在 2015 年 6 月至 2015 年 12 月实施适当的阿片类药物处方多模式教育活动之后)进行了回顾。根据记录的 9 项内容计算了阿片类药物适当性评分。使用 Fisher 确切检验分析分类变量,使用 2 样本 t 检验和回归分析分析连续变量。使用二元逻辑回归进行多变量建模。使用 Mann-Whitney 检验比较干预前后的适当性评分。

结果

分别在基线和干预后评估了 177 例和 96 例患者。患者的人口统计学特征没有统计学差异。总体而言,干预后适当性水平与干预前明显不同(<.0001),平均得分从干预前的 5.54 增加到干预后的 6.29。两个诊所的基线水平都有显著改善(两个 P 值均<.003)。

结论

治疗 CNCP 时,对最佳实践的临床医生教育与阿片类药物使用适当性水平的提高相关。

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