Department of Pharmacy, Harborview Medical Center, University of Washington, Seattle.
School of Pharmacy, University of Washington, Seattle.
Clin Infect Dis. 2020 Mar 3;70(6):1230-1232. doi: 10.1093/cid/ciz646.
Cross-reactivity should be considered when treating patients with a previous hypersensitivity reaction within the same class of antibiotics that share similar chemical structures. This case report describes a patient with severe hypersensitivity reaction to vancomycin who successfully tolerated a dalbavancin graded challenge.
在治疗同一类抗生素中曾发生过过敏反应的患者时,应考虑交叉反应,这些抗生素具有相似的化学结构。本病例报告描述了一位对万古霉素严重过敏反应的患者成功耐受了达巴万星的梯度挑战。