School of Natural Sciences, The University of Zambia, PO Box 32379, Lusaka, 10101, Zambia.
Department of Disease Control, School of Veterinary Medicine, The University of Zambia, PO Box 32379, Lusaka, 10101, Zambia.
Arch Virol. 2019 Oct;164(10):2531-2536. doi: 10.1007/s00705-019-04350-6. Epub 2019 Jul 12.
Whilst bovine leukemia virus (BLV) causes considerable economic losses to the dairy industry worldwide, information on its molecular epidemiology and economic impact in beef cattle is limited. Here, blood from 880 animals from Zambia's major cattle-rearing provinces was screened for BLV by nested PCR. Positive pools were sequenced and phylogenetically analyzed. The estimated pooled prevalence was 2.1%. All strains belonged to genotype 1 and formed a distinct phylogenetic cluster. The study suggests circulation of genotype 1 BLV in beef cattle in these regions. This is the first report on molecular detection and characterization of BLV from beef cattle in Africa.
虽然牛白血病病毒（BLV）给世界范围内的奶制品行业造成了巨大的经济损失，但有关其在肉牛中的分子流行病学和经济影响的信息却很有限。在这里，通过巢式 PCR 对来自赞比亚主要养牛省份的 880 头动物的血液进行了 BLV 筛查。对阳性池进行了测序和系统进化分析。估计的总流行率为 2.1%。所有毒株均属于基因型 1，形成了一个独特的系统进化群。该研究表明，在这些地区的肉牛中存在基因型 1 BLV 的传播。这是首次在非洲从肉牛中检测和鉴定 BLV 的分子特征。
