有效肉毒毒素注射治疗颈肌张力障碍指南。
Effective botulinum toxin injection guide for treatment of cervical dystonia.
机构信息
School of Medicine, The Catholic University of Korea, Seoul, South Korea.
Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Center, BK21 PLUS Project, Yonsei University College of Dentistry, Seoul, South Korea.
出版信息
Clin Anat. 2020 Mar;33(2):192-198. doi: 10.1002/ca.23430. Epub 2019 Jul 25.
The aim of this study was to elucidate the distribution of the accessory nerve within the sternocleidomastoid muscle (SCM) to aid identifying the optimum sites for botulinum neurotoxin (BoNT) injections and applying chemical neurolysis. Thirty SCM specimens from 15 Korean cadavers were used in this study. Sihler's staining was applied to 10 of the SCM specimens. Transverse lines were drawn in 20 sections to divide the SCM into 10 divisions vertically, and a vertical line was drawn into the medial and lateral halves from the mastoid process to the sternoclavicular joint. The most densely innervated areas were 5/10-6/10 and 6/10-7/10 along the lateral and medial parts of the muscle, respectively. We suggest injecting BoNT in the medial region 6/10-7/10 along the SCM prior to injecting in the lateral region 5/10-6/10 along the muscle to ensure safe and effective treatment. Clin. Anat. 33:192-198, 2020. © 2019 Wiley Periodicals, Inc.
本研究旨在阐明副神经在胸锁乳突肌（SCM）中的分布，以帮助确定肉毒毒素（BoNT）注射的最佳部位和应用化学神经松解术。本研究使用了 15 具韩国尸体的 30 块 SCM 标本。对其中 10 块 SCM 标本进行了 Sihler 染色。在 20 个切片中画出横线，将 SCM 垂直分为 10 部分，从乳突到胸锁关节在肌肉的内外侧各画一条竖线。最密集的神经支配区域分别是肌肉外侧的 5/10-6/10 和内侧的 6/10-7/10。我们建议在注射 SCM 外侧的 5/10-6/10 区域之前，先在 SCM 内侧的 6/10-7/10 区域注射 BoNT，以确保安全有效的治疗。临床解剖学 33:192-198, 2020. © 2019 Wiley Periodicals, Inc.
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