Faculdade de Odontologia São Leopoldo Mandic, Rua José Rocha Junqueira 13, Campinas, 13045-755, SP, Brazil.
Faculdade de Odontologia São Leopoldo Mandic, Rua José Rocha Junqueira 13, Campinas, 13045-755, SP, Brazil.
Photodiagnosis Photodyn Ther. 2019 Sep;27:396-401. doi: 10.1016/j.pdpdt.2019.07.002. Epub 2019 Jul 10.
This study aimed to determine the effects of photodynamic therapy (PDT) on postoperative pain after treatments of teeth with necrotic pulps. This randomized clinical trial consisted of 60 patients who presented for treatment of asymptomatic teeth. The patients were randomly assigned into the Control Group (CG) or the PDT Group (PG). The canals were instrumented with a reciprocating instrument (50.05) under 2.5% NaOCL irrigation. After instrumentation was completed, the canals were flooded with 1.56 μM/mL of methylene blue (MB), the optical fiber was inserted to the working length and applied for 3 min (P =100 mW, t =3 min, E = 18 J). The device emitted PDT only for the PG. The operator and the patient were both masked to the treatment protocol. After PDT, the root canal treatment was completed and the canals were filled. A card was given to the patients to document their pain perception through the 0-10 visual analogue scale (VAS) at 24 h, 72 h, and 1-week intervals. The Mann-Whitney and Fisher´s exact tests were used for statistical analysis (P < .05). The average pain level for the CG was 1.33 at 24 -hs and 0.50 at 72 -hs; for the PG, the average pain level was 0.37 at 24 -h and 0 at 72 -h (P < .05). After 1-week there was no report of pain. PDT had a significant effect in decreasing postoperative pain at 24- and 72 -h intervals in treatment of single-rooted teeth with necrotic pulps performed in one visit.
本研究旨在确定光动力疗法（PDT）对治疗坏死牙髓牙齿后术后疼痛的影响。这是一项随机临床试验，纳入了 60 名因无症状牙齿就诊的患者。患者随机分为对照组（CG）或 PDT 组（PG）。根管使用 2.5%次氯酸钠冲洗下的往复式器械进行预备。器械预备完成后，根管内充满 1.56 μM/mL 的亚甲蓝（MB），将光纤插入工作长度并照射 3 分钟（P = 100 mW，t = 3 分钟，E = 18 J）。仅对 PG 实施 PDT。操作员和患者均对治疗方案设盲。PDT 后，完成根管治疗并填充根管。给患者一张卡片，让他们通过 0-10 视觉模拟评分（VAS）记录 24 小时、72 小时和 1 周间隔的疼痛感知。采用曼-惠特尼和 Fisher 精确检验进行统计学分析（P <.05）。CG 的平均疼痛水平在 24 小时时为 1.33，在 72 小时时为 0.50；PG 的平均疼痛水平在 24 小时时为 0.37，在 72 小时时为 0（P <.05）。1 周后无疼痛报告。在单次就诊治疗单个根的坏死牙髓牙齿时，PDT 可显著降低 24 小时和 72 小时的术后疼痛。
