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兴奋谵妄综合征的三例尸检病例报告——简短比较。

Three postmortem case reports of the excited delirium syndrome - A short comparison.

作者信息

Śliwicka Olga, Szatner Karolina, Borowska-Solonynko Aleksandra

机构信息

Forensic Medicine Student Scientific Group, Department of Forensic Medicine, Medical University of Warsaw, Ul. W. Oczki 1, 02-007, Warsaw, Poland.

Forensic Medicine Student Scientific Group, Department of Forensic Medicine, Medical University of Warsaw, Ul. W. Oczki 1, 02-007, Warsaw, Poland.

出版信息

J Forensic Leg Med. 2019 Aug;66:134-137. doi: 10.1016/j.jflm.2019.06.013. Epub 2019 Jun 27.

Abstract

PURPOSE

The purpose of the work is to show and compare three reported cases of Excited Delirium Syndrome, which happened in Warsaw, Poland, from 2013 to 2017. We compared the results of three autopsy and toxicological findings of unexpectedly deceased males and the circumstances of their death, based on the police records.

RESULTS

There were no significant findings of chronic diseases or multiple traumas leading us to the clear explanation of cause of death. We noted a rapid cardiopulmonary failure accompanied by drug abuse in all three cases, that happened following a stressful stimulus, evoked by a police restraint in prone position. All patients resembled similar external characteristics and BMI and had used drugs before death.

CONCLUSION

A lack of the autopsy findings suggests the Excited Delirium Syndrome as a cause of death. The syndrome may be diagnosed after death, following the definition of exclusion of other somatic causes of death, preceded by symptoms during a stressful event. The syndrome occurs in overweight males, abusing especially stimulants. The physical restraint plays an important role in the initiation of the symptoms. The pathophysiology of the syndrome is poorly understood, but some theories underline dopamine transporters stimulation. To this day, there are no published Excited Delirium guidelines for forensic specialists or pathologists.

摘要

目的

本研究旨在展示并比较2013年至2017年发生在波兰华沙的三例兴奋谵妄综合征报告病例。我们根据警方记录,对比了三名意外死亡男性的尸检结果、毒理学发现及其死亡情况。

结果

未发现导致明确死因的慢性疾病或多处创伤的显著证据。我们注意到,在所有三例病例中,均出现了快速心肺功能衰竭并伴有药物滥用,这发生在因警方俯卧位约束引发的应激刺激之后。所有患者都有相似的外部特征和体重指数,且在死亡前均使用过药物。

结论

缺乏尸检结果表明兴奋谵妄综合征可能是死因。在排除其他躯体性死因后,根据应激事件期间出现的症状定义,该综合征可在死后诊断。该综合征发生于超重男性,尤其滥用兴奋剂者。身体约束在症状引发中起重要作用。该综合征的病理生理学尚不清楚,但一些理论强调多巴胺转运体刺激。时至今日,尚未有针对法医专家或病理学家的兴奋谵妄指南发表。

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