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改良俯卧位与右侧卧位经皮椎体后凸成形术治疗肥胖合并慢性阻塞性肺疾病伴疼痛性骨质疏松性椎体压缩骨折的初步研究。

Preliminary Study of Obese Patients with Chronic Obstructive Pulmonary Disease Suffering from Painful Osteoporotic Vertebral Compression Fracture Treated by Percutaneous Vertebroplasty in Improved Prone Position and Right Lateral Position.

机构信息

Department of Orthopedics, Beijing Friendship Hospital Capital Medical University, Beijing, China.

Department of Emergency, Beijing Friendship Hospital Capital Medical University, Beijing, China.

出版信息

World Neurosurg. 2019 Oct;130:e933-e940. doi: 10.1016/j.wneu.2019.07.040. Epub 2019 Jul 11.

DOI:10.1016/j.wneu.2019.07.040
PMID:31302276
Abstract

OBJECTIVE

To assess outcomes in obese patients with chronic obstructive pulmonary disease (COPD) who sustained an osteoporotic vertebral compression fracture (OVCF) treated by percutaneous vertebroplasty (PVP) in the improved prone position and right lateral position.

METHODS

Between January 2015 and May 2016, a total of 60 patients were enrolled in this randomized controlled study. Patients in group A were placed in the improved prone position for a bilateral transpedicular technique, and those in group B were placed in the right lateral position for a left transverse process-pedicle approach. Clinical and radiologic outcomes were assessed and compared between the 2 groups during the 12-month follow-up period.

RESULTS

All operations were successfully completed without any serious sequelae. The operation time, fluoroscopic time, scores for respiratory condition during the operation, intravertebral cement volume, and incidence of cement leakage were significantly greater in group A compared with group B (P < 0.01). During the follow-up period, all patients in both groups experienced significant improvement in pain relief. Satisfactory functional improvement was obtained at 3 months postoperatively.

CONCLUSIONS

Treatment of obese patients with COPD suffering from painful OVCF by PVP in both the improved prone position with a bilateral technique and the right lateral position with a unilateral technique was relatively safe and effective. However, unilateral PVP in the right lateral position was associated with a shorter operation time, limited fluoroscopic time, and minimal cement leakage.

摘要

目的

评估肥胖合并慢性阻塞性肺疾病(COPD)患者经皮椎体成形术(PVP)治疗骨质疏松性椎体压缩性骨折(OVCF)的预后,这些患者在改良俯卧位和右侧侧卧位下接受手术。

方法

2015 年 1 月至 2016 年 5 月,共有 60 例患者纳入本随机对照研究。A 组患者采用改良俯卧位双侧经椎弓根技术,B 组患者采用右侧侧卧位左侧横突-椎弓根入路。在 12 个月的随访期间,评估并比较两组患者的临床和影像学结果。

结果

所有手术均顺利完成,无严重并发症。A 组患者的手术时间、透视时间、术中呼吸状况评分、椎体内骨水泥量和骨水泥渗漏发生率明显高于 B 组(P<0.01)。在随访期间,两组患者的疼痛缓解均有显著改善。术后 3 个月获得满意的功能改善。

结论

对于肥胖合并 COPD 且患有疼痛性 OVCF 的患者,采用改良俯卧位双侧技术和右侧侧卧位单侧技术行 PVP 治疗均相对安全有效。然而,右侧侧卧位单侧 PVP 具有手术时间更短、透视时间有限和骨水泥渗漏最小的特点。

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